Gene detail

B2C47_RS00535

Histidine kinase, Classic

Clostridioides difficile · GCF_900165335

ClassHKTypeClassicLength686 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900165335#B2C47_RS00535Stable P2CS identifier used across views.
GenomeGCF_900165335Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0802381Run 6 · 6 sequences · id 100% · cov 80%
External referencesWP_176072451.1 · MIST4 B2C47_RS00535RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length686 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 686 aa (23.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for B2C47_RS00535
Domain-by-domain annotation2 items
1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw tokenHisKA:457:0.0000000000000298:524:68:64
2 HATPase_c#2
570-663 aa · 94 aa · 13.7% of protein
Raw tokenHATPase_c:570:0.000000000000726:663:98:109
  • Raw architecture: HisKA:457:0.0000000000000298:524:68:64#HATPase_c:570:0.000000000000726:663:98:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900165335::NZ_FUQB01000001.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span118197-121145Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375148_00107RefSeq proteinWP_176072451.1
Context group IDGCF_900165335::NZ_FUQB01000001.1::G00042
Context members
B2C47_RS00525B2C47_RS00535
Partner locus tags
B2C47_RS00525B2C47_RS00535
Partner old locus tags
SAMEA3375148_00106SAMEA3375148_00107
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_176072451.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C47_RS00535Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375148_00107Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUQB01000001.1Sequence record reported by the local genomic context database.
Genomic interval119 085-121 145 nt2 061 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span118 197-121 145 ntGCF_900165335::NZ_FUQB01000001.1::G00042

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165335::NZ_FUQB01000001.1::G00042

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUQB01000001.1All displayed genes belong to this local TCS context.
Neighborhood span118 197-121 145 nt2 949 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
118 197 nt121 145 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2C47_RS00525GCF_900165335#B2C47_RS00525
RROmpR

118 197-118 889 nt · Forward (+)

Old locus SAMEA3375148_00106RefSeq WP_004454566.1
B2C47_RS00535GCF_900165335#B2C47_RS00535
HKClassicCurrent focus

119 085-121 145 nt · Forward (+)

Old locus SAMEA3375148_00107RefSeq WP_176072451.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0802381Run 6 · HK · 6 sequences
Representative sequenceGCF_025534015#H3U72_RS01070Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0802381

Simplified PFAM architecture for HKOC_0802381

PFAM domain coverage: 160 / 686 aa (23.3%)

1 aa686 aa
HisKA: 457-524 aaHisKAHATPase_c: 571-662 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[457-524] | HATPase_c[571-662]
  • Domain count: 2
  • Matched identifier: HKOC_0802381
  • Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Visualization

Representative gene: GCF_025534015#H3U72_RS01070

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165335
Assembly16780_8#82 · Scaffoldhaploid
Genome composition4 281 476 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 50 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key