Gene detail

QZL78_RS05445

Histidine kinase, Classic

uncultured Blautia sp. · GCF_900066335

ClassHKTypeClassicLength596 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900066335#QZL78_RS05445Stable P2CS identifier used across views.
GenomeGCF_900066335Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1076055Run 6 · 28 sequences · id 100% · cov 80%
External referencesWP_021976597.1 · A0AAW5CIG8 · MIST4 QZL78_RS05445RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length596 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage491 / 596 aa (82.4%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa596 aa
dCache_1: 47-289 aa (243 aa)1HAMP: 308-377 aa (70 aa)2His_kinase: 392-469 aa (78 aa)3HATPase_c: 493-592 aa (100 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
47-289 aa · 243 aa · 40.8% of protein
Raw tokendCache_1:47:0.0000000000209:289:243:195
2 HAMP#2
308-377 aa · 70 aa · 11.7% of protein
Raw tokenHAMP:308:0.000000000109:377:70:69
3 His_kinase#3
392-469 aa · 78 aa · 13.1% of protein
Raw tokenHis_kinase:392:3.33e-30:469:78:80
4 HATPase_c#4
493-592 aa · 100 aa · 16.8% of protein
Raw tokenHATPase_c:493:0.00000000000000832:592:104:109
  • Raw architecture: dCache_1:47:0.0000000000209:289:243:195#HAMP:308:0.000000000109:377:70:69#His_kinase:392:3.33e-30:469:78:80#HATPase_c:493:0.00000000000000832:592:104:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900066335::NZ_FMEU01000004.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span205977-209375Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3545288_01080RefSeq proteinWP_021976597.1
Context group IDGCF_900066335::NZ_FMEU01000004.1::G00017
Context members
QZL78_RS05445QZL78_RS05450
Partner locus tags
QZL78_RS05445QZL78_RS05450
Partner old locus tags
SAMEA3545288_01080SAMEA3545288_01081
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021976597.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW5CIG8Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW5CIG8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQZL78_RS05445Primary locus identifier stored in the genes table.
Old locus tagSAMEA3545288_01080Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FMEU01000004.1Sequence record reported by the local genomic context database.
Genomic interval205 977-207 767 nt1 791 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span205 977-209 375 ntGCF_900066335::NZ_FMEU01000004.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900066335::NZ_FMEU01000004.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FMEU01000004.1All displayed genes belong to this local TCS context.
Neighborhood span205 977-209 375 nt3 399 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
205 977 nt209 375 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QZL78_RS05445GCF_900066335#QZL78_RS05445
HKClassicCurrent focus

205 977-207 767 nt · Forward (+)

Old locus SAMEA3545288_01080RefSeq WP_021976597.1
QZL78_RS05450GCF_900066335#QZL78_RS05450
RRunclassified

207 786-209 375 nt · Forward (+)

Old locus SAMEA3545288_01081RefSeq WP_173734169.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1076055Run 6 · HK · 28 sequences
Representative sequenceGCF_013302305#G5A91_RS06490Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1076055

Simplified PFAM architecture for HKOC_1076055

PFAM domain coverage: 229 / 596 aa (38.4%)

1 aa596 aa
HAMP: 328-376 aaHAMPHis_kinase: 392-469 aaHis_kinaseHATPase_c: 493-594 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[328-376] | His_kinase[392-469] | HATPase_c[493-594]
  • Domain count: 3
  • Matched identifier: HKOC_1076055
  • Positioned domains: HAMP 328-376 ; His_kinase 392-469 ; HATPase_c 493-594
Cluster members and taxonomy
Visualization

Representative gene: GCF_013302305#G5A91_RS06490

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 765 821 · GCF_900066335
Assembly13414_6#64 · Scaffoldhaploid
Genome composition3 557 791 bp · 44,0% GCuncultured Blautia sp.
Signal transduction countsGenes 78 · HK 38 · RR 38CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key