1 HAMP#1
145-212 aa · 68 aa · 15.3% of protein
Raw token
HAMP:145:0.0000000000443:212:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
AAIS09_RS10340
Histidine kinase, Classic
Streptococcus pneumoniae · GCF_041228315
ClassHKTypeClassicLength443 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_041228315#AAIS09_RS10340Stable P2CS identifier used across views.
GenomeGCF_041228315Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length443 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage234 / 443 aa (52.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa443 aa
Domain-by-domain annotation3 items
2 HisKA#2
232-297 aa · 66 aa · 14.9% of protein
Raw token
HisKA:232:0.000000000569:297:66:643 HATPase_c#3
344-443 aa · 100 aa · 22.6% of protein
Raw token
HATPase_c:344:0.000000000000604:443:104:109- Raw architecture: HAMP:145:0.0000000000443:212:68:69#HisKA:232:0.000000000569:297:66:64#HATPase_c:344:0.000000000000604:443:104:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_041228315::NZ_CP154595.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2027812-2029793Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAAIS09_10325RefSeq proteinWP_000594665.1
Context group ID
GCF_041228315::NZ_CP154595.1::G00014Context members
AAIS09_RS10340AAIS09_RS10345
Partner locus tags
AAIS09_RS10340AAIS09_RS10345
Partner old locus tags
AAIS09_10325AAIS09_10330
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000594665.1Primary protein accession used for annex mappings.
UniProt accessionC1CBG8Primary UniProt accession resolved in the annex database.
UniProt IDC1CBG8_STRP7Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagAAIS09_RS10340Primary locus identifier stored in the genes table.
Old locus tagAAIS09_10325Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP154595.1Sequence record reported by the local genomic context database.
Genomic interval2 027 812-2 029 143 nt1 332 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 027 812-2 029 793 ntGCF_041228315::NZ_CP154595.1::G00014
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_041228315::NZ_CP154595.1::G00014Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP154595.1All displayed genes belong to this local TCS context.
Neighborhood span2 027 812-2 029 793 nt1 982 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 027 812 nt2 029 793 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
AAIS09_RS10340GCF_041228315#AAIS09_RS10340
HKClassicCurrent focus
2 027 812-2 029 143 nt · Reverse (-)
AAIS09_RS10345GCF_041228315#AAIS09_RS10345
RROmpR
2 029 140-2 029 793 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007045#SPR_RS10175Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2041490
Simplified PFAM architecture for HKOC_2041490
PFAM domain coverage: 212 / 443 aa (47.9%)
1 aa443 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[162-213] | HisKA[233-296] | HATPase_c[344-439]
- Domain count: 3
- Matched identifier: HKOC_2041490
- Positioned domains: HAMP 162-213 ; HisKA 233-296 ; HATPase_c 344-439
Cluster members and taxonomy
Representative gene: GCF_000007045#SPR_RS10175
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 313 · GCF_041228315
Assembly20238042 · Complete Genomehaploid
Genome composition2 075 787 bp · 40,0% GCStreptococcus pneumoniae
Signal transduction countsGenes 29 · HK 14 · RR 15CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus
Related genes
Preview from the same derived genome key