1 Response_reg#1
4-112 aa · 109 aa · 25.5% of protein
Raw token
Response_reg:4:9.36e-28:112:109:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
AAIS09_RS00860
Response regulator, unclassified
Streptococcus pneumoniae · GCF_041228315
ClassRRTypeunclassifiedLength428 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_041228315#AAIS09_RS00860Stable P2CS identifier used across views.
GenomeGCF_041228315Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Domain signature
Compact overview inferred from the domain field
Response_regHTH_AraC
Protein length428 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage148 / 428 aa (34.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 HTH_AraCSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa428 aa
Domain-by-domain annotation2 items
2 HTH_AraC#2
384-422 aa · 39 aa · 9.1% of protein
Raw token
HTH_AraC:384:0.000000000585:422:39:42- Raw architecture: Response_reg:4:9.36e-28:112:109:111#HTH_AraC:384:0.000000000585:422:39:42
- Domain description: 1 Response_reg,1 HTH_AraC
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_041228315::NZ_CP154595.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span159345-162313Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAAIS09_00855RefSeq proteinWP_000278876.1
Context group ID
GCF_041228315::NZ_CP154595.1::G00002Context members
AAIS09_RS00855AAIS09_RS00860
Partner locus tags
AAIS09_RS00855AAIS09_RS00860
Partner old locus tags
AAIS09_00850AAIS09_00855
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000278876.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H2UN24Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H2UN24_STRPNDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagAAIS09_RS00860Primary locus identifier stored in the genes table.
Old locus tagAAIS09_00855Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP154595.1Sequence record reported by the local genomic context database.
Genomic interval161 027-162 313 nt1 287 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span159 345-162 313 ntGCF_041228315::NZ_CP154595.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_041228315::NZ_CP154595.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP154595.1All displayed genes belong to this local TCS context.
Neighborhood span159 345-162 313 nt2 969 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
159 345 nt162 313 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
AAIS09_RS00855GCF_041228315#AAIS09_RS00855
HKClassic
159 345-161 015 nt · Forward (+)
AAIS09_RS00860GCF_041228315#AAIS09_RS00860
RRunclassifiedCurrent focus
161 027-162 313 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000006885#SP_RS00805Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + HTH_182 domains in the representative PFAM annotation.
PFAM architecture for RROC_0346656
Simplified PFAM architecture for RROC_0346656
PFAM domain coverage: 190 / 428 aa (44.4%)
1 aa428 aa
Response_regHTH_18
- Simplified architecture: Response_reg + HTH_18
- Raw architecture: Response_reg[4-114] | HTH_18[345-423]
- Domain count: 2
- Matched identifier: RROC_0346656
- Positioned domains: Response_reg 4-114 ; Response_reg 4-114 ; HTH_18 345-423 ; HTH_18 345-423
Cluster members and taxonomy
Representative gene: GCF_000006885#SP_RS00805
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 313 · GCF_041228315
Assembly20238042 · Complete Genomehaploid
Genome composition2 075 787 bp · 40,0% GCStreptococcus pneumoniae
Signal transduction countsGenes 29 · HK 14 · RR 15CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus
Related genes
Preview from the same derived genome key