1 Response_reg#1
3-114 aa · 112 aa · 56.3% of protein
Raw token
Response_reg:3:1.54e-22:114:112:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
AAIS09_RS09250
Response regulator NarL family
Streptococcus pneumoniae · GCF_041228315
ClassRRTypeNarLLength199 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_041228315#AAIS09_RS09250Stable P2CS identifier used across views.
GenomeGCF_041228315Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Domain signature
Compact overview inferred from the domain field
Response_regHTH_LUXR
Protein length199 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 199 aa (85.4%)Merged over positioned domains only.
Domain description1 Response_reg,1 HTH_LUXRSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa199 aa
Domain-by-domain annotation2 items
2 HTH_LUXR#2
136-193 aa · 58 aa · 29.1% of protein
Raw token
HTH_LUXR:136:1.63e-21:193:58:58- Raw architecture: Response_reg:3:1.54e-22:114:112:111#HTH_LUXR:136:1.63e-21:193:58:58
- Domain description: 1 Response_reg,1 HTH_LUXR
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_041228315::NZ_CP154595.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1822896-1824594Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAAIS09_09235RefSeq proteinWP_000866724.1
Context group ID
GCF_041228315::NZ_CP154595.1::G00012Context members
AAIS09_RS09250AAIS09_RS09255
Partner locus tags
AAIS09_RS09250AAIS09_RS09255
Partner old locus tags
AAIS09_09235AAIS09_09240
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000866724.1Primary protein accession used for annex mappings.
UniProt accessionC1CA46Primary UniProt accession resolved in the annex database.
UniProt IDC1CA46_STRP7Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagAAIS09_RS09250Primary locus identifier stored in the genes table.
Old locus tagAAIS09_09235Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP154595.1Sequence record reported by the local genomic context database.
Genomic interval1 822 896-1 823 495 nt600 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 822 896-1 824 594 ntGCF_041228315::NZ_CP154595.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_041228315::NZ_CP154595.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP154595.1All displayed genes belong to this local TCS context.
Neighborhood span1 822 896-1 824 594 nt1 699 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 822 896 nt1 824 594 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
AAIS09_RS09250GCF_041228315#AAIS09_RS09250
RRNarLCurrent focus
1 822 896-1 823 495 nt · Reverse (-)
AAIS09_RS09255GCF_041228315#AAIS09_RS09255
HKClassic
1 823 497-1 824 594 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000018965#SP70585_RS10300Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + GerE2 domains in the representative PFAM annotation.
PFAM architecture for RROC_2143450
Simplified PFAM architecture for RROC_2143450
PFAM domain coverage: 168 / 199 aa (84.4%)
1 aa199 aa
Response_regGerE
- Simplified architecture: Response_reg + GerE
- Raw architecture: Response_reg[3-114] | GerE[138-193]
- Domain count: 2
- Matched identifier: RROC_2143450
- Positioned domains: Response_reg 3-114 ; Response_reg 3-114 ; GerE 138-193 ; GerE 138-193
Cluster members and taxonomy
Representative gene: GCF_000018965#SP70585_RS10300
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 313 · GCF_041228315
Assembly20238042 · Complete Genomehaploid
Genome composition2 075 787 bp · 40,0% GCStreptococcus pneumoniae
Signal transduction countsGenes 29 · HK 14 · RR 15CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus
Related genes
Preview from the same derived genome key