1 dCache_1#1
35-263 aa · 229 aa · 40.7% of protein
Raw token
dCache_1:35:1.33e-19:263:240:195P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
AAIS09_RS03015
Histidine kinase, Classic
Streptococcus pneumoniae · GCF_041228315
ClassHKTypeClassicLength563 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_041228315#AAIS09_RS03015Stable P2CS identifier used across views.
GenomeGCF_041228315Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Domain signature
Compact overview inferred from the domain field
dCache_1HAMPHis_kinaseHATPase_c
Protein length563 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage473 / 563 aa (84.0%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa563 aa
Domain-by-domain annotation4 items
2 HAMP#2
280-349 aa · 70 aa · 12.4% of protein
Raw token
HAMP:280:0.00000000000276:349:71:693 His_kinase#3
365-443 aa · 79 aa · 14.0% of protein
Raw token
His_kinase:365:1.96e-33:443:79:804 HATPase_c#4
463-557 aa · 95 aa · 16.9% of protein
Raw token
HATPase_c:463:0.000000000000199:557:104:109- Raw architecture: dCache_1:35:1.33e-19:263:240:195#HAMP:280:0.00000000000276:349:71:69#His_kinase:365:1.96e-33:443:79:80#HATPase_c:463:0.000000000000199:557:104:109
- Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_041228315::NZ_CP154595.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span593211-595636Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAAIS09_03010RefSeq proteinWP_000831078.1
Context group ID
GCF_041228315::NZ_CP154595.1::G00007Context members
AAIS09_RS03010AAIS09_RS03015
Partner locus tags
AAIS09_RS03010AAIS09_RS03015
Partner old locus tags
AAIS09_03005AAIS09_03010
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000831078.1Primary protein accession used for annex mappings.
UniProt accessionQ8DQN7Primary UniProt accession resolved in the annex database.
UniProt IDQ8DQN7_STRR6Display identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagAAIS09_RS03015Primary locus identifier stored in the genes table.
Old locus tagAAIS09_03010Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP154595.1Sequence record reported by the local genomic context database.
Genomic interval593 945-595 636 nt1 692 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span593 211-595 636 ntGCF_041228315::NZ_CP154595.1::G00007
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_041228315::NZ_CP154595.1::G00007Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP154595.1All displayed genes belong to this local TCS context.
Neighborhood span593 211-595 636 nt2 426 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
593 211 nt595 636 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
AAIS09_RS03010GCF_041228315#AAIS09_RS03010
RRunclassified
593 211-593 948 nt · Forward (+)
AAIS09_RS03015GCF_041228315#AAIS09_RS03015
HKClassicCurrent focus
593 945-595 636 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007045#SPR_RS02935Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1244629
Simplified PFAM architecture for HKOC_1244629
PFAM domain coverage: 452 / 563 aa (80.3%)
1 aa563 aa
dCache_1HAMPHis_kinaseHATPase_c
- Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
- Raw architecture: dCache_1[36-262] | HAMP[300-348] | His_kinase[365-443] | HATPase_c[461-557]
- Domain count: 4
- Matched identifier: HKOC_1244629
- Positioned domains: dCache_1 36-262 ; HAMP 300-348 ; His_kinase 365-443 ; HATPase_c 461-557
Cluster members and taxonomy
Representative gene: GCF_000007045#SPR_RS02935
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 313 · GCF_041228315
Assembly20238042 · Complete Genomehaploid
Genome composition2 075 787 bp · 40,0% GCStreptococcus pneumoniae
Signal transduction countsGenes 29 · HK 14 · RR 15CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus
Related genes
Preview from the same derived genome key