1 His_kinase#1
347-425 aa · 79 aa · 14.2% of protein
Raw token
His_kinase:347:5.31e-25:425:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
AAIS09_RS00855
Histidine kinase, Classic
Streptococcus pneumoniae · GCF_041228315
ClassHKTypeClassicLength556 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_041228315#AAIS09_RS00855Stable P2CS identifier used across views.
GenomeGCF_041228315Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length556 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage188 / 556 aa (33.8%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa556 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
445-553 aa · 109 aa · 19.6% of protein
Raw token
HATPase_c:445:0.0000000242:553:109:109- Raw architecture: His_kinase:347:5.31e-25:425:80:80#HATPase_c:445:0.0000000242:553:109:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_041228315::NZ_CP154595.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span159345-162313Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAAIS09_00850RefSeq proteinWP_000800582.1
Context group ID
GCF_041228315::NZ_CP154595.1::G00002Context members
AAIS09_RS00855AAIS09_RS00860
Partner locus tags
AAIS09_RS00855AAIS09_RS00860
Partner old locus tags
AAIS09_00850AAIS09_00855
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000800582.1Primary protein accession used for annex mappings.
UniProt accessionA0A6I3UJS9Primary UniProt accession resolved in the annex database.
UniProt IDA0A6I3UJS9_STREEDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagAAIS09_RS00855Primary locus identifier stored in the genes table.
Old locus tagAAIS09_00850Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP154595.1Sequence record reported by the local genomic context database.
Genomic interval159 345-161 015 nt1 671 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span159 345-162 313 ntGCF_041228315::NZ_CP154595.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_041228315::NZ_CP154595.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP154595.1All displayed genes belong to this local TCS context.
Neighborhood span159 345-162 313 nt2 969 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
159 345 nt162 313 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
AAIS09_RS00855GCF_041228315#AAIS09_RS00855
HKClassicCurrent focus
159 345-161 015 nt · Forward (+)
AAIS09_RS00860GCF_041228315#AAIS09_RS00860
RRunclassified
161 027-162 313 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000026665#SPN23F_RS00870Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1271818
Simplified PFAM architecture for HKOC_1271818
PFAM domain coverage: 188 / 556 aa (33.8%)
1 aa556 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[347-424] | HATPase_c[445-554]
- Domain count: 2
- Matched identifier: HKOC_1271818
- Positioned domains: His_kinase 347-424 ; HATPase_c 445-554
Cluster members and taxonomy
Representative gene: GCF_000026665#SPN23F_RS00870
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 313 · GCF_041228315
Assembly20238042 · Complete Genomehaploid
Genome composition2 075 787 bp · 40,0% GCStreptococcus pneumoniae
Signal transduction countsGenes 29 · HK 14 · RR 15CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus
Related genes
Preview from the same derived genome key