1 Response_reg#1
5-109 aa · 105 aa · 43.6% of protein
Raw token
Response_reg:5:1.57e-28:109:106:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SQ528_RS12575
Response regulator OmpR family
Clostridioides difficile · GCF_034188315
ClassRRTypeOmpRLength241 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_034188315#SQ528_RS12575Stable P2CS identifier used across views.
GenomeGCF_034188315Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
Response_regTrans_reg_C
Protein length241 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage182 / 241 aa (75.5%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa241 aa
Domain-by-domain annotation2 items
2 Trans_reg_C#2
160-236 aa · 77 aa · 32.0% of protein
Raw token
Trans_reg_C:160:2.41e-32:236:77:77- Raw architecture: Response_reg:5:1.57e-28:109:106:111#Trans_reg_C:160:2.41e-32:236:77:77
- Domain description: 1 Response_reg,1 Trans_reg_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_034188315::NZ_JAXHRE010000030.1::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4180-6312Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSQ528_12565RefSeq proteinWP_004454491.1
Context group ID
GCF_034188315::NZ_JAXHRE010000030.1::G00034Context members
SQ528_RS12575SQ528_RS12580
Partner locus tags
SQ528_RS12575SQ528_RS12580
Partner old locus tags
SQ528_12565SQ528_12570
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_004454491.1Primary protein accession used for annex mappings.
UniProt accessionQ186M7Primary UniProt accession resolved in the annex database.
UniProt IDQ186M7_CLOD6Display identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSQ528_RS12575Primary locus identifier stored in the genes table.
Old locus tagSQ528_12565Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAXHRE010000030.1Sequence record reported by the local genomic context database.
Genomic interval4 180-4 905 nt726 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 180-6 312 ntGCF_034188315::NZ_JAXHRE010000030.1::G00034
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_034188315::NZ_JAXHRE010000030.1::G00034Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAXHRE010000030.1All displayed genes belong to this local TCS context.
Neighborhood span4 180-6 312 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 180 nt6 312 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SQ528_RS12575GCF_034188315#SQ528_RS12575
RROmpRCurrent focus
4 180-4 905 nt · Forward (+)
SQ528_RS12580GCF_034188315#SQ528_RS12580
HKClassic
4 909-6 312 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_022359795#MJO50_RS17260Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0632387
Simplified PFAM architecture for RROC_0632387
PFAM domain coverage: 184 / 265 aa (69.4%)
1 aa265 aa
Response_regTrans_reg_C
- Simplified architecture: Response_reg + Trans_reg_C
- Raw architecture: Response_reg[29-135] | Trans_reg_C[184-260]
- Domain count: 2
- Matched identifier: RROC_0632387
- Positioned domains: Response_reg 29-135 ; Trans_reg_C 184-260
Cluster members and taxonomy
Representative gene: GCF_022359795#MJO50_RS17260
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_034188315
AssemblyASM3418831v1 · Contighaploid
Genome composition4 239 228 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key