Gene detail

SQ528_RS00515

Histidine kinase, Classic

Clostridioides difficile · GCF_034188315

ClassHKTypeClassicLength912 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_034188315#SQ528_RS00515Stable P2CS identifier used across views.
GenomeGCF_034188315Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0387805Run 6 · 595 sequences · id 100% · cov 80%
External referencesWP_004454784.1 · Q182H8 · MIST4 SQ528_RS00515RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_9HisKAHATPase_c
Protein length912 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage284 / 912 aa (31.1%)Merged over positioned domains only.
Domain description1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa912 aa
PAS_9: 529-629 aa (101 aa)1HisKA: 655-726 aa (72 aa)2HATPase_c: 773-883 aa (111 aa)3
Domain-by-domain annotation3 items
1 PAS_9#1
529-629 aa · 101 aa · 11.1% of protein
Raw tokenPAS_9:529:0.0000748:629:101:102
2 HisKA#2
655-726 aa · 72 aa · 7.9% of protein
Raw tokenHisKA:655:0.00000000000000668:726:72:64
3 HATPase_c#3
773-883 aa · 111 aa · 12.2% of protein
Raw tokenHATPase_c:773:3.38e-31:883:111:109
  • Raw architecture: PAS_9:529:0.0000748:629:101:102#HisKA:655:0.00000000000000668:726:72:64#HATPase_c:773:3.38e-31:883:111:109
  • Domain description: 1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_034188315::NZ_JAXHRE010000001.1::G00001
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span110141-112879Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSQ528_00515RefSeq proteinWP_004454784.1
Context group IDGCF_034188315::NZ_JAXHRE010000001.1::G00001
Context members
SQ528_RS00515
Partner locus tags
SQ528_RS00515
Partner old locus tags
SQ528_00515
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004454784.1Primary protein accession used for annex mappings.
UniProt accessionQ182H8Primary UniProt accession resolved in the annex database.
UniProt IDQ182H8_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSQ528_RS00515Primary locus identifier stored in the genes table.
Old locus tagSQ528_00515Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAXHRE010000001.1Sequence record reported by the local genomic context database.
Genomic interval110 141-112 879 nt2 739 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span110 141-112 879 ntGCF_034188315::NZ_JAXHRE010000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_034188315::NZ_JAXHRE010000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAXHRE010000001.1All displayed genes belong to this local TCS context.
Neighborhood span110 141-112 879 nt2 739 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
110 141 nt112 879 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

SQ528_RS00515GCF_034188315#SQ528_RS00515
HKClassicCurrent focus

110 141-112 879 nt · Reverse (-)

Old locus SQ528_00515RefSeq WP_004454784.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0387805Run 6 · HK · 595 sequences
Representative sequenceGCF_000009205#CD630_RS13390Use this link to inspect the representative gene detail.
PFAM architecturePAS_8 + PAS_9 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0387805

Simplified PFAM architecture for HKOC_0387805

PFAM domain coverage: 340 / 912 aa (37.3%)

1 aa912 aa
PAS_8: 303-355 aaPAS_8PAS_9: 529-632 aaPAS_9HisKA: 655-726 aaHisKAHATPase_c: 773-883 aaHATPase_c
PAS_8PAS_9HisKAHATPase_c
  • Simplified architecture: PAS_8 + PAS_9 + HisKA + HATPase_c
  • Raw architecture: PAS_8[303-355] | PAS_9[529-632] | HisKA[655-726] | HATPase_c[773-883]
  • Domain count: 4
  • Matched identifier: HKOC_0387805
  • Positioned domains: PAS_8 303-355 ; PAS_9 529-632 ; HisKA 655-726 ; HATPase_c 773-883
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS13390

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_034188315
AssemblyASM3418831v1 · Contighaploid
Genome composition4 239 228 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key