Gene detail

PNW85_RS02735

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_028327205

ClassHKTypeClassicLength571 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_028327205#PNW85_RS02735Stable P2CS identifier used across views.
GenomeGCF_028327205Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1210008Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_272107771.1 · A0AAW6D8H5 · MIST4 PNW85_RS02735RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length571 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage430 / 571 aa (75.3%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa571 aa
dCache_1: 42-221 aa (180 aa)1HAMP: 281-347 aa (67 aa)2His_kinase: 362-441 aa (80 aa)3HATPase_c: 458-560 aa (103 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
42-221 aa · 180 aa · 31.5% of protein
Raw tokendCache_1:42:0.00000347:221:181:195
2 HAMP#2
281-347 aa · 67 aa · 11.7% of protein
Raw tokenHAMP:281:0.0000000000112:347:67:69
3 His_kinase#3
362-441 aa · 80 aa · 14.0% of protein
Raw tokenHis_kinase:362:2.14e-28:441:80:80
4 HATPase_c#4
458-560 aa · 103 aa · 18.0% of protein
Raw tokenHATPase_c:458:0.000000000000168:560:112:109
  • Raw architecture: dCache_1:42:0.00000347:221:181:195#HAMP:281:0.0000000000112:347:67:69#His_kinase:362:2.14e-28:441:80:80#HATPase_c:458:0.000000000000168:560:112:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_028327205::NZ_JAQMLA010000005.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span22621-25846Genomic interval covered by the local TCS group.
Identifiers
Old locus tagPNW85_02735RefSeq proteinWP_272107771.1
Context group IDGCF_028327205::NZ_JAQMLA010000005.1::G00039
Context members
PNW85_RS02730PNW85_RS02735
Partner locus tags
PNW85_RS02730PNW85_RS02735
Partner old locus tags
PNW85_02730PNW85_02735
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_272107771.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW6D8H5Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW6D8H5_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagPNW85_RS02735Primary locus identifier stored in the genes table.
Old locus tagPNW85_02735Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAQMLA010000005.1Sequence record reported by the local genomic context database.
Genomic interval24 131-25 846 nt1 716 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span22 621-25 846 ntGCF_028327205::NZ_JAQMLA010000005.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_028327205::NZ_JAQMLA010000005.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAQMLA010000005.1All displayed genes belong to this local TCS context.
Neighborhood span22 621-25 846 nt3 226 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
22 621 nt25 846 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

PNW85_RS02730GCF_028327205#PNW85_RS02730
RRunclassified

22 621-24 159 nt · Forward (+)

Old locus PNW85_02730RefSeq WP_173882648.1
PNW85_RS02735GCF_028327205#PNW85_RS02735
HKClassicCurrent focus

24 131-25 846 nt · Forward (+)

Old locus PNW85_02735RefSeq WP_272107771.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1210008Run 6 · HK · 6 sequences
Representative sequenceGCF_028327205#PNW85_RS02735The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1210008

Simplified PFAM architecture for HKOC_1210008

PFAM domain coverage: 230 / 571 aa (40.3%)

1 aa571 aa
HAMP: 295-346 aaHAMPHis_kinase: 363-439 aaHis_kinaseHATPase_c: 459-559 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[295-346] | His_kinase[363-439] | HATPase_c[459-559]
  • Domain count: 3
  • Matched identifier: HKOC_1210008
  • Positioned domains: HAMP 295-346 ; His_kinase 363-439 ; HATPase_c 459-559
Cluster members and taxonomy
Visualization

Representative gene: GCF_028327205#PNW85_RS02735

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_028327205
AssemblyASM2832720v1 · Scaffoldhaploid
Genome composition4 221 822 bp · 42,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 101 · HK 45 · RR 52CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key