1 HisKA#1
140-199 aa · 60 aa · 16.4% of protein
Raw token
HisKA:140:0.000000000268:199:60:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NB459_RS00275
Histidine kinase, Classic
Clostridioides difficile · GCF_023656905
ClassHKTypeClassicLength365 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_023656905#NB459_RS00275Stable P2CS identifier used across views.
GenomeGCF_023656905Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length365 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage166 / 365 aa (45.5%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa365 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
256-361 aa · 106 aa · 29.0% of protein
Raw token
HATPase_c:256:4.12e-27:361:106:109- Raw architecture: HisKA:140:0.000000000268:199:60:64#HATPase_c:256:4.12e-27:361:106:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_023656905::NZ_JAMOJV010000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span30891-32727Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNB459_00275RefSeq proteinWP_236887088.1
Context group ID
GCF_023656905::NZ_JAMOJV010000001.1::G00001Context members
NB459_RS00275NB459_RS00280
Partner locus tags
NB459_RS00275NB459_RS00280
Partner old locus tags
NB459_00275NB459_00280
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_236887088.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNB459_RS00275Primary locus identifier stored in the genes table.
Old locus tagNB459_00275Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAMOJV010000001.1Sequence record reported by the local genomic context database.
Genomic interval30 891-31 988 nt1 098 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span30 891-32 727 ntGCF_023656905::NZ_JAMOJV010000001.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_023656905::NZ_JAMOJV010000001.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAMOJV010000001.1All displayed genes belong to this local TCS context.
Neighborhood span30 891-32 727 nt1 837 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
30 891 nt32 727 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NB459_RS00275GCF_023656905#NB459_RS00275
HKClassicCurrent focus
30 891-31 988 nt · Reverse (-)
NB459_RS00280GCF_023656905#NB459_RS00280
RROmpR
31 993-32 727 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002891605#AMR89_RS13385Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2719747
Simplified PFAM architecture for HKOC_2719747
PFAM domain coverage: 167 / 365 aa (45.8%)
1 aa365 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[140-199] | HATPase_c[256-362]
- Domain count: 2
- Matched identifier: HKOC_2719747
- Positioned domains: HisKA 140-199 ; HATPase_c 256-362
Cluster members and taxonomy
Representative gene: GCF_002891605#AMR89_RS13385
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_023656905
AssemblyASM2365690v1 · Scaffoldhaploid
Genome composition4 229 501 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key