Gene detail

D0C48_RS05730

Histidine kinase, Classic

Faecalibacterium prausnitzii · GCF_022750565

ClassHKTypeClassicLength455 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_022750565#D0C48_RS05730Stable P2CS identifier used across views.
GenomeGCF_022750565Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Faecalibacterium
Selected clusterHKOC_1899594Run 6 · 12 sequences · id 100% · cov 80%
External referencesWP_005922225.1 · A8S892 · MIST4 D0C48_RS05730RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length455 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage236 / 455 aa (51.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa455 aa
HAMP: 159-225 aa (67 aa)1HisKA: 236-302 aa (67 aa)2HATPase_c: 351-452 aa (102 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
159-225 aa · 67 aa · 14.7% of protein
Raw tokenHAMP:159:0.00000221:225:69:69
2 HisKA#2
236-302 aa · 67 aa · 14.7% of protein
Raw tokenHisKA:236:0.00000000000437:302:67:64
3 HATPase_c#3
351-452 aa · 102 aa · 22.4% of protein
Raw tokenHATPase_c:351:6.48e-18:452:106:109
  • Raw architecture: HAMP:159:0.00000221:225:69:69#HisKA:236:0.00000000000437:302:67:64#HATPase_c:351:6.48e-18:452:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_022750565::NZ_QVIH01000003.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span149131-151214Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD0C48_05730RefSeq proteinWP_005922225.1
Context group IDGCF_022750565::NZ_QVIH01000003.1::G00009
Context members
D0C48_RS05730D0C48_RS05735
Partner locus tags
D0C48_RS05730D0C48_RS05735
Partner old locus tags
D0C48_05730D0C48_05735
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_005922225.1Primary protein accession used for annex mappings.
UniProt accessionA8S892Primary UniProt accession resolved in the annex database.
UniProt IDA8S892_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD0C48_RS05730Primary locus identifier stored in the genes table.
Old locus tagD0C48_05730Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QVIH01000003.1Sequence record reported by the local genomic context database.
Genomic interval149 131-150 498 nt1 368 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span149 131-151 214 ntGCF_022750565::NZ_QVIH01000003.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_022750565::NZ_QVIH01000003.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QVIH01000003.1All displayed genes belong to this local TCS context.
Neighborhood span149 131-151 214 nt2 084 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
149 131 nt151 214 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

D0C48_RS05730GCF_022750565#D0C48_RS05730
HKClassicCurrent focus

149 131-150 498 nt · Reverse (-)

Old locus D0C48_05730RefSeq WP_005922225.1
D0C48_RS05735GCF_022750565#D0C48_RS05735
RROmpR

150 495-151 214 nt · Reverse (-)

Old locus D0C48_05735RefSeq WP_113621247.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1899594Run 6 · HK · 12 sequences
Representative sequenceGCF_000154385#FAEPRAM212_RS04535Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1899594

Simplified PFAM architecture for HKOC_1899594

PFAM domain coverage: 169 / 455 aa (37.1%)

1 aa455 aa
HisKA: 236-302 aaHisKAHATPase_c: 351-452 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[236-302] | HATPase_c[351-452]
  • Domain count: 2
  • Matched identifier: HKOC_1899594
  • Positioned domains: HisKA 236-302 ; HATPase_c 351-452
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154385#FAEPRAM212_RS04535

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 853 · GCF_022750565
AssemblyASM2275056v1 · Contighaploid
Genome composition3 243 905 bp · 56,0% GCFaecalibacterium prausnitzii
Signal transduction countsGenes 50 · HK 23 · RR 26CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusFaecalibacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Faecalibacterium

Related genes

Preview from the same derived genome key