Gene detail

LKD46_RS16410

Histidine kinase, Classic

Blautia fusiformis · GCF_020686995

ClassHKTypeClassicLength567 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_020686995#LKD46_RS16410Stable P2CS identifier used across views.
GenomeGCF_020686995Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1217470Run 6 · 57 sequences · id 100% · cov 80%
External referencesWP_021650824.1 · A0AAW4W446 · MIST4 LKD46_RS16410RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length567 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 567 aa (43.6%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa567 aa
HAMP: 283-349 aa (67 aa)1His_kinase: 365-443 aa (79 aa)2HATPase_c: 461-561 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
283-349 aa · 67 aa · 11.8% of protein
Raw tokenHAMP:283:0.0000000000203:349:67:69
2 His_kinase#2
365-443 aa · 79 aa · 13.9% of protein
Raw tokenHis_kinase:365:2.77e-27:443:79:80
3 HATPase_c#3
461-561 aa · 101 aa · 17.8% of protein
Raw tokenHATPase_c:461:0.0000000000128:561:110:109
  • Raw architecture: HAMP:283:0.0000000000203:349:67:69#His_kinase:365:2.77e-27:443:79:80#HATPase_c:461:0.0000000000128:561:110:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_020686995::NZ_JAJEPT010000032.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8417-11633Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLKD46_16480RefSeq proteinWP_021650824.1
Context group IDGCF_020686995::NZ_JAJEPT010000032.1::G00035
Context members
LKD46_RS16405LKD46_RS16410
Partner locus tags
LKD46_RS16405LKD46_RS16410
Partner old locus tags
LKD46_16475LKD46_16480
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021650824.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW4W446Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW4W446_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLKD46_RS16410Primary locus identifier stored in the genes table.
Old locus tagLKD46_16480Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJEPT010000032.1Sequence record reported by the local genomic context database.
Genomic interval9 930-11 633 nt1 704 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span8 417-11 633 ntGCF_020686995::NZ_JAJEPT010000032.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_020686995::NZ_JAJEPT010000032.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJEPT010000032.1All displayed genes belong to this local TCS context.
Neighborhood span8 417-11 633 nt3 217 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 417 nt11 633 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LKD46_RS16405GCF_020686995#LKD46_RS16405
RRunclassified

8 417-9 955 nt · Forward (+)

Old locus LKD46_16475RefSeq WP_059085412.1
LKD46_RS16410GCF_020686995#LKD46_RS16410
HKClassicCurrent focus

9 930-11 633 nt · Forward (+)

Old locus LKD46_16480RefSeq WP_021650824.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1217470Run 6 · HK · 57 sequences
Representative sequenceGCF_003184505#DMI82_RS19165Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1217470

Simplified PFAM architecture for HKOC_1217470

PFAM domain coverage: 227 / 569 aa (39.9%)

1 aa569 aa
HAMP: 301-350 aaHAMPHis_kinase: 367-443 aaHis_kinaseHATPase_c: 464-563 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[301-350] | His_kinase[367-443] | HATPase_c[464-563]
  • Domain count: 3
  • Matched identifier: HKOC_1217470
  • Positioned domains: HAMP 301-350 ; His_kinase 367-443 ; HATPase_c 464-563
Cluster members and taxonomy
Visualization

Representative gene: GCF_003184505#DMI82_RS19165

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 881 264 · GCF_020686995
AssemblyASM2068699v1 · Contigreference genome · haploid
Genome composition3 534 643 bp · 44,0% GCBlautia fusiformis
Signal transduction countsGenes 91 · HK 41 · RR 48CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key