1 HAMP#1
176-244 aa · 69 aa · 11.7% of protein
Raw token
HAMP:176:0.00000000000000509:244:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EXW59_RS12570
Histidine kinase, Classic
Bacillus mycoides · GCF_018741465
ClassHKTypeClassicLength591 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018741465#EXW59_RS12570Stable P2CS identifier used across views.
Domain signature
Compact overview inferred from the domain field
HAMPPASHisKAHATPase_c
Protein length591 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage348 / 591 aa (58.9%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa591 aa
Domain-by-domain annotation4 items
2 PAS#2
255-355 aa · 101 aa · 17.1% of protein
Raw token
PAS:255:0.0000117:355:113:1133 HisKA#3
364-431 aa · 68 aa · 11.5% of protein
Raw token
HisKA:364:3.88e-18:431:68:644 HATPase_c#4
478-587 aa · 110 aa · 18.6% of protein
Raw token
HATPase_c:478:1.36e-33:587:110:109- Raw architecture: HAMP:176:0.00000000000000509:244:69:69#PAS:255:0.0000117:355:113:113#HisKA:364:3.88e-18:431:68:64#HATPase_c:478:1.36e-33:587:110:109
- Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018741465::NZ_CP036084.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1545827-1548318Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEXW59_12875RefSeq proteinWP_002011760.1
Context group ID
GCF_018741465::NZ_CP036084.1::G00020Context members
EXW59_RS12565EXW59_RS12570
Partner locus tags
EXW59_RS12565EXW59_RS12570
Partner old locus tags
EXW59_12870EXW59_12875
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002011760.1Primary protein accession used for annex mappings.
UniProt accessionA9VLP5Primary UniProt accession resolved in the annex database.
UniProt IDA9VLP5_BACMKDisplay identifier provided by UniProt.
GO / PubMed7 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEXW59_RS12570Primary locus identifier stored in the genes table.
Old locus tagEXW59_12875Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP036084.1Sequence record reported by the local genomic context database.
Genomic interval1 546 543-1 548 318 nt1 776 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 545 827-1 548 318 ntGCF_018741465::NZ_CP036084.1::G00020
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018741465::NZ_CP036084.1::G00020Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP036084.1All displayed genes belong to this local TCS context.
Neighborhood span1 545 827-1 548 318 nt2 492 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 545 827 nt1 548 318 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EXW59_RS12565GCF_018741465#EXW59_RS12565
RROmpR
1 545 827-1 546 543 nt · Forward (+)
EXW59_RS12570GCF_018741465#EXW59_RS12570
HKClassicCurrent focus
1 546 543-1 548 318 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000018825#BCERKBAB4_RS07380Use this link to inspect the representative gene detail.
PFAM architectureHisK_sensor + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1105082
Simplified PFAM architecture for HKOC_1105082
PFAM domain coverage: 357 / 591 aa (60.4%)
1 aa591 aa
HisK_sensorHAMPHisKAHATPase_c
- Simplified architecture: HisK_sensor + HAMP + HisKA + HATPase_c
- Raw architecture: HisK_sensor[38-163] | HAMP[193-244] | HisKA[364-431] | HATPase_c[478-588]
- Domain count: 4
- Matched identifier: HKOC_1105082
- Positioned domains: HisK_sensor 38-163 ; HAMP 193-244 ; HisKA 364-431 ; HATPase_c 478-588
Cluster members and taxonomy
Representative gene: GCF_000018825#BCERKBAB4_RS07380
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 405 · GCF_018741465
AssemblyASM1874146v1 · Complete Genomehaploid
Genome composition6 338 271 bp · 35,5% GCBacillus mycoides
Signal transduction countsGenes 126 · HK 68 · RR 58CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus
Related genes
Preview from the same derived genome key