Gene detail

I2G75_RS08470

Histidine kinase, Classic

Roseburia faecis · GCF_015558055

ClassHKTypeClassicLength607 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015558055#I2G75_RS08470Stable P2CS identifier used across views.
GenomeGCF_015558055Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_1019181Run 6 · 4 sequences · id 100% · cov 80%
External referencesWP_022046038.1 · A0A0M6WDH7 · MIST4 I2G75_RS08470RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length607 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage254 / 607 aa (41.8%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa607 aa
HAMP: 289-358 aa (70 aa)1His_kinase: 380-459 aa (80 aa)2HATPase_c: 483-586 aa (104 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
289-358 aa · 70 aa · 11.5% of protein
Raw tokenHAMP:289:0.0000000053:358:70:69
2 His_kinase#2
380-459 aa · 80 aa · 13.2% of protein
Raw tokenHis_kinase:380:1.3e-31:459:80:80
3 HATPase_c#3
483-586 aa · 104 aa · 17.1% of protein
Raw tokenHATPase_c:483:0.00000123:586:105:109
  • Raw architecture: HAMP:289:0.0000000053:358:70:69#His_kinase:380:1.3e-31:459:80:80#HATPase_c:483:0.00000123:586:105:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015558055::NZ_JADNPM010000010.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span76357-79763Genomic interval covered by the local TCS group.
Context group IDGCF_015558055::NZ_JADNPM010000010.1::G00005
Context members
I2G75_RS08470I2G75_RS08475
Partner locus tags
I2G75_RS08470I2G75_RS08475
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_022046038.1Primary protein accession used for annex mappings.
UniProt accessionA0A0M6WDH7Primary UniProt accession resolved in the annex database.
UniProt IDA0A0M6WDH7_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI2G75_RS08470Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADNPM010000010.1Sequence record reported by the local genomic context database.
Genomic interval76 357-78 180 nt1 824 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span76 357-79 763 ntGCF_015558055::NZ_JADNPM010000010.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015558055::NZ_JADNPM010000010.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADNPM010000010.1All displayed genes belong to this local TCS context.
Neighborhood span76 357-79 763 nt3 407 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
76 357 nt79 763 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

I2G75_RS08475GCF_015558055#I2G75_RS08475
RRunclassified

78 174-79 763 nt · Forward (+)

RefSeq WP_022046039.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1019181Run 6 · HK · 4 sequences
Representative sequenceGCF_001406815#M72_RS01225Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1019181

Simplified PFAM architecture for HKOC_1019181

PFAM domain coverage: 237 / 607 aa (39.0%)

1 aa607 aa
HAMP: 306-356 aaHAMPHis_kinase: 380-459 aaHis_kinaseHATPase_c: 481-586 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[306-356] | His_kinase[380-459] | HATPase_c[481-586]
  • Domain count: 3
  • Matched identifier: HKOC_1019181
  • Positioned domains: HAMP 306-356 ; His_kinase 380-459 ; HATPase_c 481-586
Cluster members and taxonomy
Visualization

Representative gene: GCF_001406815#M72_RS01225

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 301 302 · GCF_015558055
AssemblyASM1555805v1 · Scaffoldhaploid
Genome composition3 915 225 bp · 42,5% GCRoseburia faecis
Signal transduction countsGenes 117 · HK 49 · RR 66CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key