Gene detail

I2G75_RS01585

Histidine kinase, CheA

Roseburia faecis · GCF_015558055

ClassHKTypeCheALength698 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015558055#I2G75_RS01585Stable P2CS identifier used across views.
GenomeGCF_015558055Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_0773315Run 6 · 3 sequences · id 100% · cov 80%
External referencesWP_055263702.1 · A0A173UCK7 · MIST4 I2G75_RS01585RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length698 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage425 / 698 aa (60.9%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa698 aa
Hpt: 5-97 aa (93 aa)1H-kinase_dim: 316-379 aa (64 aa)2HATPase_c: 427-566 aa (140 aa)3CheW: 571-698 aa (128 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
5-97 aa · 93 aa · 13.3% of protein
Raw tokenHpt:5:1.8e-17:97:93:84
2 H-kinase_dim#2
316-379 aa · 64 aa · 9.2% of protein
Raw tokenH-kinase_dim:316:7.47e-16:379:67:67
3 HATPase_c#3
427-566 aa · 140 aa · 20.1% of protein
Raw tokenHATPase_c:427:0.00000000000000115:566:140:109
4 CheW#4
571-698 aa · 128 aa · 18.3% of protein
Raw tokenCheW:571:2.72e-30:698:135:138
  • Raw architecture: Hpt:5:1.8e-17:97:93:84#H-kinase_dim:316:7.47e-16:379:67:67#HATPase_c:427:0.00000000000000115:566:140:109#CheW:571:2.72e-30:698:135:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015558055::NZ_JADNPM010000002.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span24848-28010Genomic interval covered by the local TCS group.
Context group IDGCF_015558055::NZ_JADNPM010000002.1::G00038
Context members
I2G75_RS01580I2G75_RS01585
Partner locus tags
I2G75_RS01580I2G75_RS01585
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055263702.1Primary protein accession used for annex mappings.
UniProt accessionA0A173UCK7Primary UniProt accession resolved in the annex database.
UniProt IDA0A173UCK7_9FIRMDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI2G75_RS01585Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADNPM010000002.1Sequence record reported by the local genomic context database.
Genomic interval25 914-28 010 nt2 097 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span24 848-28 010 ntGCF_015558055::NZ_JADNPM010000002.1::G00038

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015558055::NZ_JADNPM010000002.1::G00038

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADNPM010000002.1All displayed genes belong to this local TCS context.
Neighborhood span24 848-28 010 nt3 163 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
24 848 nt28 010 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

I2G75_RS01580GCF_015558055#I2G75_RS01580
RRCheB

24 848-25 912 nt · Forward (+)

RefSeq WP_055263833.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0773315Run 6 · HK · 3 sequences
Representative sequenceGCF_001405615#ARB75_RS14055Use this link to inspect the representative gene detail.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0773315

Simplified PFAM architecture for HKOC_0773315

PFAM domain coverage: 500 / 698 aa (71.6%)

1 aa698 aa
Hpt: 5-97 aaHptP2: 182-257 aaP2H-kinase_dim: 315-379 aaH-kinase_dimHATPase_c: 428-566 aaHATPase_cCheW: 571-697 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[5-97] | P2[182-257] | H-kinase_dim[315-379] | HATPase_c[428-566] | CheW[571-697]
  • Domain count: 5
  • Matched identifier: HKOC_0773315
  • Positioned domains: Hpt 5-97 ; P2 182-257 ; H-kinase_dim 315-379 ; HATPase_c 428-566 ; CheW 571-697
Cluster members and taxonomy
Visualization

Representative gene: GCF_001405615#ARB75_RS14055

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 301 302 · GCF_015558055
AssemblyASM1555805v1 · Scaffoldhaploid
Genome composition3 915 225 bp · 42,5% GCRoseburia faecis
Signal transduction countsGenes 117 · HK 49 · RR 66CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key