Gene detail

H8S80_RS00070

Histidine kinase, Classic

Hungatella sp. L36 · GCF_014288035

ClassHKTypeClassicLength594 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_014288035#H8S80_RS00070Stable P2CS identifier used across views.
GenomeGCF_014288035Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_1087213Run 6 · 27 sequences · id 100% · cov 80%
External referencesWP_002600936.1 · A0A6N3I8W1 · MIST4 H8S80_RS00070RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length594 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage364 / 594 aa (61.3%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa594 aa
dCache_1: 184-293 aa (110 aa)1HAMP: 311-377 aa (67 aa)2His_kinase: 394-473 aa (80 aa)3HATPase_c: 485-591 aa (107 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
184-293 aa · 110 aa · 18.5% of protein
Raw tokendCache_1:184:0.0000000868:293:113:195
2 HAMP#2
311-377 aa · 67 aa · 11.3% of protein
Raw tokenHAMP:311:0.0000000052:377:67:69
3 His_kinase#3
394-473 aa · 80 aa · 13.5% of protein
Raw tokenHis_kinase:394:1.27e-28:473:80:80
4 HATPase_c#4
485-591 aa · 107 aa · 18.0% of protein
Raw tokenHATPase_c:485:1.24e-17:591:114:109
  • Raw architecture: dCache_1:184:0.0000000868:293:113:195#HAMP:311:0.0000000052:377:67:69#His_kinase:394:1.27e-28:473:80:80#HATPase_c:485:1.24e-17:591:114:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_014288035::NZ_JACOPC010000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span9818-13124Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH8S80_00070RefSeq proteinWP_002600936.1
Context group IDGCF_014288035::NZ_JACOPC010000001.1::G00001
Context members
H8S80_RS00070H8S80_RS00075
Partner locus tags
H8S80_RS00070H8S80_RS00075
Partner old locus tags
H8S80_00070H8S80_00075
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002600936.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N3I8W1Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N3I8W1_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH8S80_RS00070Primary locus identifier stored in the genes table.
Old locus tagH8S80_00070Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACOPC010000001.1Sequence record reported by the local genomic context database.
Genomic interval9 818-11 602 nt1 785 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span9 818-13 124 ntGCF_014288035::NZ_JACOPC010000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_014288035::NZ_JACOPC010000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACOPC010000001.1All displayed genes belong to this local TCS context.
Neighborhood span9 818-13 124 nt3 307 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 818 nt13 124 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

H8S80_RS00070GCF_014288035#H8S80_RS00070
HKClassicCurrent focus

9 818-11 602 nt · Reverse (-)

Old locus H8S80_00070RefSeq WP_002600936.1
H8S80_RS00075GCF_014288035#H8S80_RS00075
RRunclassified

11 586-13 124 nt · Reverse (-)

Old locus H8S80_00075RefSeq WP_002600935.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1087213Run 6 · HK · 27 sequences
Representative sequenceGCF_000371445#HMPREF1093_RS05590Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1087213

Simplified PFAM architecture for HKOC_1087213

PFAM domain coverage: 428 / 594 aa (72.1%)

1 aa594 aa
dCache_1: 49-292 aadCache_1His_kinase: 395-473 aaHis_kinaseHATPase_c: 488-592 aaHATPase_c
dCache_1His_kinaseHATPase_c
  • Simplified architecture: dCache_1 + His_kinase + HATPase_c
  • Raw architecture: dCache_1[49-292] | His_kinase[395-473] | HATPase_c[488-592]
  • Domain count: 3
  • Matched identifier: HKOC_1087213
  • Positioned domains: dCache_1 49-292 ; His_kinase 395-473 ; HATPase_c 488-592
Cluster members and taxonomy
Visualization

Representative gene: GCF_000371445#HMPREF1093_RS05590

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 763 049 · GCF_014288035
AssemblyASM1428803v1 · Contighaploid
Genome composition7 705 063 bp · 49,0% GCHungatella sp. L36
Signal transduction countsGenes 294 · HK 146 · RR 145CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key