Gene detail

H8K24_RS03925

Histidine kinase, Classic

Blautia massiliensis (ex Durand et al. 2017) · GCF_014269345

ClassHKTypeClassicLength579 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_014269345#H8K24_RS03925Stable P2CS identifier used across views.
GenomeGCF_014269345Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1168420Run 6 · 2 sequences · id 100% · cov 80%
External referencesWP_118608903.1 · MIST4 H8K24_RS03925RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length579 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage477 / 579 aa (82.4%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa579 aa
dCache_1: 36-258 aa (223 aa)1HAMP: 284-353 aa (70 aa)2His_kinase: 368-447 aa (80 aa)3HATPase_c: 464-567 aa (104 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
36-258 aa · 223 aa · 38.5% of protein
Raw tokendCache_1:36:0.00000000000599:258:223:195
2 HAMP#2
284-353 aa · 70 aa · 12.1% of protein
Raw tokenHAMP:284:0.00000000000000251:353:70:69
3 His_kinase#3
368-447 aa · 80 aa · 13.8% of protein
Raw tokenHis_kinase:368:1.36e-25:447:80:80
4 HATPase_c#4
464-567 aa · 104 aa · 18.0% of protein
Raw tokenHATPase_c:464:0.0000000000000138:567:109:109
  • Raw architecture: dCache_1:36:0.00000000000599:258:223:195#HAMP:284:0.00000000000000251:353:70:69#His_kinase:368:1.36e-25:447:80:80#HATPase_c:464:0.0000000000000138:567:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_014269345::NZ_JACOGH010000002.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span345203-348528Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH8K24_03925RefSeq proteinWP_118608903.1
Context group IDGCF_014269345::NZ_JACOGH010000002.1::G00015
Context members
H8K24_RS03920H8K24_RS03925
Partner locus tags
H8K24_RS03920H8K24_RS03925
Partner old locus tags
H8K24_03920H8K24_03925
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_118608903.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH8K24_RS03925Primary locus identifier stored in the genes table.
Old locus tagH8K24_03925Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACOGH010000002.1Sequence record reported by the local genomic context database.
Genomic interval346 789-348 528 nt1 740 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span345 203-348 528 ntGCF_014269345::NZ_JACOGH010000002.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_014269345::NZ_JACOGH010000002.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACOGH010000002.1All displayed genes belong to this local TCS context.
Neighborhood span345 203-348 528 nt3 326 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
345 203 nt348 528 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

H8K24_RS03920GCF_014269345#H8K24_RS03920
RRunclassified

345 203-346 789 nt · Reverse (-)

Old locus H8K24_03920RefSeq WP_118608904.1
H8K24_RS03925GCF_014269345#H8K24_RS03925
HKClassicCurrent focus

346 789-348 528 nt · Reverse (-)

Old locus H8K24_03925RefSeq WP_118608903.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1168420Run 6 · HK · 2 sequences
Representative sequenceGCF_003479245#DWW77_RS13660Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1168420

Simplified PFAM architecture for HKOC_1168420

PFAM domain coverage: 233 / 579 aa (40.2%)

1 aa579 aa
HAMP: 301-352 aaHAMPHis_kinase: 368-445 aaHis_kinaseHATPase_c: 466-568 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[301-352] | His_kinase[368-445] | HATPase_c[466-568]
  • Domain count: 3
  • Matched identifier: HKOC_1168420
  • Positioned domains: HAMP 301-352 ; His_kinase 368-445 ; HATPase_c 466-568
Cluster members and taxonomy
Visualization

Representative gene: GCF_003479245#DWW77_RS13660

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 737 424 · GCF_014269345
AssemblyASM1426934v1 · Contighaploid
Genome composition3 672 674 bp · 44,0% GCBlautia massiliensis (ex Durand et al. 2017)
Signal transduction countsGenes 93 · HK 44 · RR 48CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key