Gene detail

H8K24_RS00350

Histidine kinase, Classic

Blautia massiliensis (ex Durand et al. 2017) · GCF_014269345

ClassHKTypeClassicLength608 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_014269345#H8K24_RS00350Stable P2CS identifier used across views.
GenomeGCF_014269345Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1015392Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_207724822.1 · MIST4 H8K24_RS00350RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length608 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage259 / 608 aa (42.6%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa608 aa
HAMP: 300-376 aa (77 aa)1His_kinase: 393-472 aa (80 aa)2HATPase_c: 492-593 aa (102 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
300-376 aa · 77 aa · 12.7% of protein
Raw tokenHAMP:300:0.000000314:376:77:69
2 His_kinase#2
393-472 aa · 80 aa · 13.2% of protein
Raw tokenHis_kinase:393:3.6e-24:472:80:80
3 HATPase_c#3
492-593 aa · 102 aa · 16.8% of protein
Raw tokenHATPase_c:492:0.0000000000288:593:103:109
  • Raw architecture: HAMP:300:0.000000314:376:77:69#His_kinase:393:3.6e-24:472:80:80#HATPase_c:492:0.0000000000288:593:103:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_014269345::NZ_JACOGH010000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span71044-74440Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH8K24_00350RefSeq proteinWP_207724822.1
Context group IDGCF_014269345::NZ_JACOGH010000001.1::G00002
Context members
H8K24_RS00350H8K24_RS00355
Partner locus tags
H8K24_RS00350H8K24_RS00355
Partner old locus tags
H8K24_00350H8K24_00355
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_207724822.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH8K24_RS00350Primary locus identifier stored in the genes table.
Old locus tagH8K24_00350Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACOGH010000001.1Sequence record reported by the local genomic context database.
Genomic interval71 044-72 870 nt1 827 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span71 044-74 440 ntGCF_014269345::NZ_JACOGH010000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_014269345::NZ_JACOGH010000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACOGH010000001.1All displayed genes belong to this local TCS context.
Neighborhood span71 044-74 440 nt3 397 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
71 044 nt74 440 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

H8K24_RS00350GCF_014269345#H8K24_RS00350
HKClassicCurrent focus

71 044-72 870 nt · Forward (+)

Old locus H8K24_00350RefSeq WP_207724822.1
H8K24_RS00355GCF_014269345#H8K24_RS00355
RRunclassified

72 845-74 440 nt · Forward (+)

Old locus H8K24_00355RefSeq WP_021652321.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1015392Run 6 · HK · 1 sequences
Representative sequenceGCF_014269345#H8K24_RS00350The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1015392

Simplified PFAM architecture for HKOC_1015392

PFAM domain coverage: 181 / 608 aa (29.8%)

1 aa608 aa
His_kinase: 394-471 aaHis_kinaseHATPase_c: 492-594 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[394-471] | HATPase_c[492-594]
  • Domain count: 2
  • Matched identifier: HKOC_1015392
  • Positioned domains: His_kinase 394-471 ; HATPase_c 492-594
Cluster members and taxonomy
Visualization

Representative gene: GCF_014269345#H8K24_RS00350

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 737 424 · GCF_014269345
AssemblyASM1426934v1 · Contighaploid
Genome composition3 672 674 bp · 44,0% GCBlautia massiliensis (ex Durand et al. 2017)
Signal transduction countsGenes 93 · HK 44 · RR 48CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key