Gene detail

G4462_RS00400

Histidine kinase, Classic

Blautia wexlerae · GCF_013301725

ClassHKTypeClassicLength493 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013301725#G4462_RS00400Stable P2CS identifier used across views.
GenomeGCF_013301725Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1515370Run 6 · 36 sequences · id 100% · cov 80%
External referencesWP_055059352.1 · A0A174QC96 · MIST4 G4462_RS00400RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length493 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage255 / 493 aa (51.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa493 aa
HAMP: 188-254 aa (67 aa)1His_kinase: 285-364 aa (80 aa)2HATPase_c: 383-490 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
188-254 aa · 67 aa · 13.6% of protein
Raw tokenHAMP:188:0.0000000000833:254:67:69
2 His_kinase#2
285-364 aa · 80 aa · 16.2% of protein
Raw tokenHis_kinase:285:6.37e-30:364:80:80
3 HATPase_c#3
383-490 aa · 108 aa · 21.9% of protein
Raw tokenHATPase_c:383:0.00000000000019:490:108:109
  • Raw architecture: HAMP:188:0.0000000000833:254:67:69#His_kinase:285:6.37e-30:364:80:80#HATPase_c:383:0.00000000000019:490:108:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013301725::NZ_JAAIOV010000001.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span83548-86651Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4462_00400RefSeq proteinWP_055059352.1
Context group IDGCF_013301725::NZ_JAAIOV010000001.1::G00016
Context members
G4462_RS00400G4462_RS00405
Partner locus tags
G4462_RS00400G4462_RS00405
Partner old locus tags
G4462_00400G4462_00405
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055059352.1Primary protein accession used for annex mappings.
UniProt accessionA0A174QC96Primary UniProt accession resolved in the annex database.
UniProt IDA0A174QC96_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4462_RS00400Primary locus identifier stored in the genes table.
Old locus tagG4462_00400Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIOV010000001.1Sequence record reported by the local genomic context database.
Genomic interval83 548-85 029 nt1 482 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span83 548-86 651 ntGCF_013301725::NZ_JAAIOV010000001.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013301725::NZ_JAAIOV010000001.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIOV010000001.1All displayed genes belong to this local TCS context.
Neighborhood span83 548-86 651 nt3 104 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
83 548 nt86 651 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4462_RS00400GCF_013301725#G4462_RS00400
HKClassicCurrent focus

83 548-85 029 nt · Forward (+)

Old locus G4462_00400RefSeq WP_055059352.1
G4462_RS00405GCF_013301725#G4462_RS00405
RRunclassified

85 056-86 651 nt · Forward (+)

Old locus G4462_00405RefSeq WP_055052672.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1515370Run 6 · HK · 36 sequences
Representative sequenceGCF_001404755#ARA24_RS03425Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1515370

Simplified PFAM architecture for HKOC_1515370

PFAM domain coverage: 233 / 493 aa (47.3%)

1 aa493 aa
HAMP: 206-254 aaHAMPHis_kinase: 285-361 aaHis_kinaseHATPase_c: 384-490 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[206-254] | His_kinase[285-361] | HATPase_c[384-490]
  • Domain count: 3
  • Matched identifier: HKOC_1515370
  • Positioned domains: HAMP 206-254 ; His_kinase 285-361 ; HATPase_c 384-490
Cluster members and taxonomy
Visualization

Representative gene: GCF_001404755#ARA24_RS03425

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 418 240 · GCF_013301725
AssemblyASM1330172v1 · Contighaploid
Genome composition4 105 799 bp · 41,0% GCBlautia wexlerae
Signal transduction countsGenes 125 · HK 62 · RR 62CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key