1 HAMP#1
307-385 aa · 79 aa · 12.9% of protein
Raw token
HAMP:307:0.00000012:385:79:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
G4462_RS00640
Histidine kinase, Classic
Blautia wexlerae · GCF_013301725
ClassHKTypeClassicLength614 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013301725#G4462_RS00640Stable P2CS identifier used across views.
GenomeGCF_013301725Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length614 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage261 / 614 aa (42.5%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa614 aa
Domain-by-domain annotation3 items
2 His_kinase#2
400-479 aa · 80 aa · 13.0% of protein
Raw token
His_kinase:400:1.16e-23:479:80:803 HATPase_c#3
499-600 aa · 102 aa · 16.6% of protein
Raw token
HATPase_c:499:0.0000000000032:600:104:109- Raw architecture: HAMP:307:0.00000012:385:79:69#His_kinase:400:1.16e-23:479:80:80#HATPase_c:499:0.0000000000032:600:104:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_013301725::NZ_JAAIOV010000002.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2639-6062Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4462_00645RefSeq proteinWP_226824623.1
Context group ID
GCF_013301725::NZ_JAAIOV010000002.1::G00022Context members
G4462_RS00635G4462_RS00640
Partner locus tags
G4462_RS00635G4462_RS00640
Partner old locus tags
G4462_00640G4462_00645
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_226824623.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagG4462_RS00640Primary locus identifier stored in the genes table.
Old locus tagG4462_00645Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIOV010000002.1Sequence record reported by the local genomic context database.
Genomic interval4 218-6 062 nt1 845 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 639-6 062 ntGCF_013301725::NZ_JAAIOV010000002.1::G00022
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_013301725::NZ_JAAIOV010000002.1::G00022Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIOV010000002.1All displayed genes belong to this local TCS context.
Neighborhood span2 639-6 062 nt3 424 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 639 nt6 062 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
G4462_RS00635GCF_013301725#G4462_RS00635
RRunclassified
2 639-4 243 nt · Reverse (-)
G4462_RS00640GCF_013301725#G4462_RS00640
HKClassicCurrent focus
4 218-6 062 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_013299815#G4455_RS01030Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0992172
Simplified PFAM architecture for HKOC_0992172
PFAM domain coverage: 181 / 614 aa (29.5%)
1 aa614 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[401-478] | HATPase_c[499-601]
- Domain count: 2
- Matched identifier: HKOC_0992172
- Positioned domains: His_kinase 401-478 ; HATPase_c 499-601
Cluster members and taxonomy
Representative gene: GCF_013299815#G4455_RS01030
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 418 240 · GCF_013301725
AssemblyASM1330172v1 · Contighaploid
Genome composition4 105 799 bp · 41,0% GCBlautia wexlerae
Signal transduction countsGenes 125 · HK 62 · RR 62CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia
Related genes
Preview from the same derived genome key