Gene detail

G4355_RS09050

Histidine kinase, Classic

Dorea longicatena · GCF_013299835

ClassHKTypeClassicLength565 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013299835#G4355_RS09050Stable P2CS identifier used across views.
GenomeGCF_013299835Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Selected clusterHKOC_1234807Run 6 · 17 sequences · id 100% · cov 80%
External referencesWP_055181529.1 · A0A174IGB9 · MIST4 G4355_RS09050RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length565 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage466 / 565 aa (82.5%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa565 aa
dCache_1: 38-250 aa (213 aa)1HAMP: 272-342 aa (71 aa)2His_kinase: 357-436 aa (80 aa)3HATPase_c: 455-556 aa (102 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
38-250 aa · 213 aa · 37.7% of protein
Raw tokendCache_1:38:0.000000518:250:217:195
2 HAMP#2
272-342 aa · 71 aa · 12.6% of protein
Raw tokenHAMP:272:0.000000000289:342:71:69
3 His_kinase#3
357-436 aa · 80 aa · 14.2% of protein
Raw tokenHis_kinase:357:1.78e-25:436:80:80
4 HATPase_c#4
455-556 aa · 102 aa · 18.1% of protein
Raw tokenHATPase_c:455:0.000000000166:556:109:109
  • Raw architecture: dCache_1:38:0.000000518:250:217:195#HAMP:272:0.000000000289:342:71:69#His_kinase:357:1.78e-25:436:80:80#HATPase_c:455:0.000000000166:556:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013299835::NZ_JAAIMW010000013.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span40684-43888Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4355_09075RefSeq proteinWP_055181529.1
Context group IDGCF_013299835::NZ_JAAIMW010000013.1::G00006
Context members
G4355_RS09045G4355_RS09050
Partner locus tags
G4355_RS09045G4355_RS09050
Partner old locus tags
G4355_09070G4355_09075
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055181529.1Primary protein accession used for annex mappings.
UniProt accessionA0A174IGB9Primary UniProt accession resolved in the annex database.
UniProt IDA0A174IGB9_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 2Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4355_RS09050Primary locus identifier stored in the genes table.
Old locus tagG4355_09075Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIMW010000013.1Sequence record reported by the local genomic context database.
Genomic interval42 191-43 888 nt1 698 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span40 684-43 888 ntGCF_013299835::NZ_JAAIMW010000013.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013299835::NZ_JAAIMW010000013.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIMW010000013.1All displayed genes belong to this local TCS context.
Neighborhood span40 684-43 888 nt3 205 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
40 684 nt43 888 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4355_RS09045GCF_013299835#G4355_RS09045
RRunclassified

40 684-42 210 nt · Reverse (-)

Old locus G4355_09070RefSeq WP_173733587.1
G4355_RS09050GCF_013299835#G4355_RS09050
HKClassicCurrent focus

42 191-43 888 nt · Reverse (-)

Old locus G4355_09075RefSeq WP_055181529.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1234807Run 6 · HK · 17 sequences
Representative sequenceGCF_001405135#ARC33_RS07415Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1234807

Simplified PFAM architecture for HKOC_1234807

PFAM domain coverage: 374 / 565 aa (66.2%)

1 aa565 aa
dCache_1: 39-232 aadCache_1His_kinase: 357-435 aaHis_kinaseHATPase_c: 455-555 aaHATPase_c
dCache_1His_kinaseHATPase_c
  • Simplified architecture: dCache_1 + His_kinase + HATPase_c
  • Raw architecture: dCache_1[39-232] | His_kinase[357-435] | HATPase_c[455-555]
  • Domain count: 3
  • Matched identifier: HKOC_1234807
  • Positioned domains: dCache_1 39-232 ; His_kinase 357-435 ; HATPase_c 455-555
Cluster members and taxonomy
Visualization

Representative gene: GCF_001405135#ARC33_RS07415

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 88 431 · GCF_013299835
AssemblyASM1329983v1 · Contighaploid
Genome composition3 134 633 bp · 41,5% GCDorea longicatena
Signal transduction countsGenes 79 · HK 38 · RR 41CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea

Related genes

Preview from the same derived genome key