Gene detail

F2P57_RS00685

Histidine kinase, Classic

[Clostridium] symbiosum · GCF_008632235

ClassHKTypeClassicLength431 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_008632235#F2P57_RS00685Stable P2CS identifier used across views.
GenomeGCF_008632235Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_2164733Run 6 · 12 sequences · id 100% · cov 80% · representative
External referencesWP_243133657.1 · A0AAW6AS02 · MIST4 F2P57_RS00685RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length431 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 431 aa (38.7%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa431 aa
His_kinase: 245-318 aa (74 aa)1HATPase_c: 336-428 aa (93 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
245-318 aa · 74 aa · 17.2% of protein
Raw tokenHis_kinase:245:4.97e-24:318:75:80
2 HATPase_c#2
336-428 aa · 93 aa · 21.6% of protein
Raw tokenHATPase_c:336:0.00000000000509:428:105:109
  • Raw architecture: His_kinase:245:4.97e-24:318:75:80#HATPase_c:336:0.00000000000509:428:105:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_008632235::NZ_VWSY01000001.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span156575-158658Genomic interval covered by the local TCS group.
Identifiers
Old locus tagF2P57_00685RefSeq proteinWP_243133657.1
Context group IDGCF_008632235::NZ_VWSY01000001.1::G00005
Context members
F2P57_RS00685F2P57_RS00690
Partner locus tags
F2P57_RS00685F2P57_RS00690
Partner old locus tags
F2P57_00685F2P57_00690
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_243133657.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW6AS02Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW6AS02_CLOSYDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagF2P57_RS00685Primary locus identifier stored in the genes table.
Old locus tagF2P57_00685Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_VWSY01000001.1Sequence record reported by the local genomic context database.
Genomic interval156 575-157 870 nt1 296 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span156 575-158 658 ntGCF_008632235::NZ_VWSY01000001.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_008632235::NZ_VWSY01000001.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_VWSY01000001.1All displayed genes belong to this local TCS context.
Neighborhood span156 575-158 658 nt2 084 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
156 575 nt158 658 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

F2P57_RS00685GCF_008632235#F2P57_RS00685
HKClassicCurrent focus

156 575-157 870 nt · Forward (+)

Old locus F2P57_00685RefSeq WP_243133657.1
F2P57_RS00690GCF_008632235#F2P57_RS00690
RRunclassified

157 867-158 658 nt · Forward (+)

Old locus F2P57_00690RefSeq WP_150026690.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2164733Run 6 · HK · 12 sequences
Representative sequenceGCF_008632235#F2P57_RS00685The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2164733

Simplified PFAM architecture for HKOC_2164733

PFAM domain coverage: 169 / 431 aa (39.2%)

1 aa431 aa
His_kinase: 243-318 aaHis_kinaseHATPase_c: 336-428 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[243-318] | HATPase_c[336-428]
  • Domain count: 2
  • Matched identifier: HKOC_2164733
  • Positioned domains: His_kinase 243-318 ; HATPase_c 336-428
Cluster members and taxonomy
Visualization

Representative gene: GCF_008632235#F2P57_RS00685

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 512 · GCF_008632235
AssemblyASM863223v1 · Scaffoldreference genome · haploid
Genome composition5 072 209 bp · 48,0% GC[Clostridium] symbiosum
Signal transduction countsGenes 115 · HK 58 · RR 54CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key