1 His_kinase#1
122-201 aa · 80 aa · 22.9% of protein
Raw token
His_kinase:122:3.47e-32:201:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
F2P57_RS00385
Histidine kinase, Classic
[Clostridium] symbiosum · GCF_008632235
ClassHKTypeClassicLength349 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_008632235#F2P57_RS00385Stable P2CS identifier used across views.
GenomeGCF_008632235Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length349 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage187 / 349 aa (53.6%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa349 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
228-334 aa · 107 aa · 30.7% of protein
Raw token
HATPase_c:228:0.0000000000000256:334:107:109- Raw architecture: His_kinase:122:3.47e-32:201:80:80#HATPase_c:228:0.0000000000000256:334:107:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_008632235::NZ_VWSY01000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span87419-90096Genomic interval covered by the local TCS group.
Identifiers
Old locus tagF2P57_00385RefSeq proteinWP_003504606.1
Context group ID
GCF_008632235::NZ_VWSY01000001.1::G00002Context members
F2P57_RS00385F2P57_RS00390
Partner locus tags
F2P57_RS00385F2P57_RS00390
Partner old locus tags
F2P57_00385F2P57_00390
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003504606.1Primary protein accession used for annex mappings.
UniProt accessionE7GTL8Primary UniProt accession resolved in the annex database.
UniProt IDE7GTL8_CLOS6Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagF2P57_RS00385Primary locus identifier stored in the genes table.
Old locus tagF2P57_00385Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_VWSY01000001.1Sequence record reported by the local genomic context database.
Genomic interval87 419-88 468 nt1 050 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span87 419-90 096 ntGCF_008632235::NZ_VWSY01000001.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_008632235::NZ_VWSY01000001.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_VWSY01000001.1All displayed genes belong to this local TCS context.
Neighborhood span87 419-90 096 nt2 678 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
87 419 nt90 096 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
F2P57_RS00385GCF_008632235#F2P57_RS00385
HKClassicCurrent focus
87 419-88 468 nt · Reverse (-)
F2P57_RS00390GCF_008632235#F2P57_RS00390
RRunclassified
88 507-90 096 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS21960Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2800996
Simplified PFAM architecture for HKOC_2800996
PFAM domain coverage: 191 / 349 aa (54.7%)
1 aa349 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[122-201] | HATPase_c[225-335]
- Domain count: 2
- Matched identifier: HKOC_2800996
- Positioned domains: His_kinase 122-201 ; HATPase_c 225-335
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS21960
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 512 · GCF_008632235
AssemblyASM863223v1 · Scaffoldreference genome · haploid
Genome composition5 072 209 bp · 48,0% GC[Clostridium] symbiosum
Signal transduction countsGenes 115 · HK 58 · RR 54CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key