Gene detail

DN394_RS00145

Histidine kinase, Classic

Bacillus sp. BB081 · GCF_008368895

ClassHKTypeClassicLength587 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_008368895#DN394_RS00145Stable P2CS identifier used across views.
GenomeGCF_008368895Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1038026Run 6 · 33 sequences · id 100% · cov 80%
External referencesWP_001032123.1 · A0A2B5SIV0 · MIST4 DN394_RS00145RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likeHAMPPASHisKAHATPase_c
Protein length587 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage470 / 587 aa (80.1%)Merged over positioned domains only.
Domain description1 sCache_like,1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa587 aa
sCache_like: 35-149 aa (115 aa)1HAMP: 165-234 aa (70 aa)2PAS: 245-351 aa (107 aa)3HisKA: 360-427 aa (68 aa)4HATPase_c: 472-581 aa (110 aa)5
Domain-by-domain annotation5 items
1 sCache_like#1
35-149 aa · 115 aa · 19.6% of protein
Raw tokensCache_like:35:2.57e-26:149:117:114
2 HAMP#2
165-234 aa · 70 aa · 11.9% of protein
Raw tokenHAMP:165:0.00000000000791:234:70:69
3 PAS#3
245-351 aa · 107 aa · 18.2% of protein
Raw tokenPAS:245:0.0000000000000257:351:112:113
4 HisKA#4
360-427 aa · 68 aa · 11.6% of protein
Raw tokenHisKA:360:1.39e-21:427:68:64
5 HATPase_c#5
472-581 aa · 110 aa · 18.7% of protein
Raw tokenHATPase_c:472:1.02e-35:581:110:109
  • Raw architecture: sCache_like:35:2.57e-26:149:117:114#HAMP:165:0.00000000000791:234:70:69#PAS:245:0.0000000000000257:351:112:113#HisKA:360:1.39e-21:427:68:64#HATPase_c:472:1.02e-35:581:110:109
  • Domain description: 1 sCache_like,1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_008368895::NZ_QOZX01000002.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5161-7636Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDN394_00145RefSeq proteinWP_001032123.1
Context group IDGCF_008368895::NZ_QOZX01000002.1::G00020
Context members
DN394_RS00140DN394_RS00145
Partner locus tags
DN394_RS00140DN394_RS00145
Partner old locus tags
DN394_00140DN394_00145
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001032123.1Primary protein accession used for annex mappings.
UniProt accessionA0A2B5SIV0Primary UniProt accession resolved in the annex database.
UniProt IDA0A2B5SIV0_9BACIDisplay identifier provided by UniProt.
GO / PubMed7 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDN394_RS00145Primary locus identifier stored in the genes table.
Old locus tagDN394_00145Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QOZX01000002.1Sequence record reported by the local genomic context database.
Genomic interval5 873-7 636 nt1 764 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span5 161-7 636 ntGCF_008368895::NZ_QOZX01000002.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_008368895::NZ_QOZX01000002.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QOZX01000002.1All displayed genes belong to this local TCS context.
Neighborhood span5 161-7 636 nt2 476 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 161 nt7 636 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DN394_RS00140GCF_008368895#DN394_RS00140
RROmpR

5 161-5 880 nt · Forward (+)

Old locus DN394_00140RefSeq WP_001065223.1
DN394_RS00145GCF_008368895#DN394_RS00145
HKClassicCurrent focus

5 873-7 636 nt · Forward (+)

Old locus DN394_00145RefSeq WP_001032123.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1038026Run 6 · HK · 33 sequences
Representative sequenceGCF_002557205#CN554_RS06430Use this link to inspect the representative gene detail.
PFAM architecturesCache_like + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1038026

Simplified PFAM architecture for HKOC_1038026

PFAM domain coverage: 449 / 603 aa (74.5%)

1 aa603 aa
sCache_like: 33-149 aasCache_likeHAMP: 188-234 aaHAMPPAS: 245-351 aaPASHisKA: 360-426 aaHisKAHATPase_c: 472-582 aaHATPase_c
sCache_likeHAMPPASHisKAHATPase_c
  • Simplified architecture: sCache_like + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: sCache_like[33-149] | HAMP[188-234] | PAS[245-351] | HisKA[360-426] | HATPase_c[472-582]
  • Domain count: 5
  • Matched identifier: HKOC_1038026
  • Positioned domains: sCache_like 33-149 ; HAMP 188-234 ; PAS 245-351 ; HisKA 360-426 ; HATPase_c 472-582
Cluster members and taxonomy
Visualization

Representative gene: GCF_002557205#CN554_RS06430

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 217 820 · GCF_008368895
AssemblyASM836889v1 · Scaffoldhaploid
Genome composition5 442 865 bp · 35,0% GCBacillus sp. BB081
Signal transduction countsGenes 122 · HK 64 · RR 57CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key