1 HAMP#1
300-376 aa · 77 aa · 12.7% of protein
Raw token
HAMP:300:0.000000566:376:77:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DWX61_RS04860
Histidine kinase, Classic
Ruminococcus sp. AF20-12LB · GCF_003478985
ClassHKTypeClassicLength608 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003478985#DWX61_RS04860Stable P2CS identifier used across views.
GenomeGCF_003478985Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Ruminococcus
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length608 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage259 / 608 aa (42.6%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa608 aa
Domain-by-domain annotation3 items
2 His_kinase#2
393-472 aa · 80 aa · 13.2% of protein
Raw token
His_kinase:393:3.93e-24:472:80:803 HATPase_c#3
492-593 aa · 102 aa · 16.8% of protein
Raw token
HATPase_c:492:0.000000000279:593:103:109- Raw architecture: HAMP:300:0.000000566:376:77:69#His_kinase:393:3.93e-24:472:80:80#HATPase_c:492:0.000000000279:593:103:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003478985::NZ_QUGH01000003.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span106509-109905Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWX61_04860RefSeq proteinWP_270426998.1
Context group ID
GCF_003478985::NZ_QUGH01000003.1::G00033Context members
DWX61_RS04860DWX61_RS04865
Partner locus tags
DWX61_RS04860DWX61_RS04865
Partner old locus tags
DWX61_04860DWX61_04865
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_270426998.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDWX61_RS04860Primary locus identifier stored in the genes table.
Old locus tagDWX61_04860Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QUGH01000003.1Sequence record reported by the local genomic context database.
Genomic interval106 509-108 335 nt1 827 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span106 509-109 905 ntGCF_003478985::NZ_QUGH01000003.1::G00033
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003478985::NZ_QUGH01000003.1::G00033Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QUGH01000003.1All displayed genes belong to this local TCS context.
Neighborhood span106 509-109 905 nt3 397 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
106 509 nt109 905 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DWX61_RS04860GCF_003478985#DWX61_RS04860
HKClassicCurrent focus
106 509-108 335 nt · Forward (+)
DWX61_RS04865GCF_003478985#DWX61_RS04865
RRunclassified
108 310-109 905 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003478985#DWX61_RS04860The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1014564
Simplified PFAM architecture for HKOC_1014564
PFAM domain coverage: 181 / 608 aa (29.8%)
1 aa608 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[394-471] | HATPase_c[492-594]
- Domain count: 2
- Matched identifier: HKOC_1014564
- Positioned domains: His_kinase 394-471 ; HATPase_c 492-594
Cluster members and taxonomy
Representative gene: GCF_003478985#DWX61_RS04860
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 2 293 160 · GCF_003478985
AssemblyASM347898v1 · Scaffoldhaploid
Genome composition3 953 478 bp · 43,5% GCRuminococcus sp. AF20-12LB
Signal transduction countsGenes 107 · HK 50 · RR 55CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusRuminococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Ruminococcus
Related genes
Preview from the same derived genome key