Gene detail

DWX61_RS04400

Histidine kinase, Classic

Ruminococcus sp. AF20-12LB · GCF_003478985

ClassHKTypeClassicLength595 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003478985#DWX61_RS04400Stable P2CS identifier used across views.
GenomeGCF_003478985Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Ruminococcus
Selected clusterHKOC_1081878Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_244790316.1 · MIST4 DWX61_RS04400RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length595 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage452 / 595 aa (76.0%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa595 aa
dCache_1: 72-276 aa (205 aa)1HAMP: 311-377 aa (67 aa)2His_kinase: 393-471 aa (79 aa)3HATPase_c: 489-589 aa (101 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
72-276 aa · 205 aa · 34.5% of protein
Raw tokendCache_1:72:0.000022:276:213:195
2 HAMP#2
311-377 aa · 67 aa · 11.3% of protein
Raw tokenHAMP:311:0.0000000000253:377:67:69
3 His_kinase#3
393-471 aa · 79 aa · 13.3% of protein
Raw tokenHis_kinase:393:2.09e-27:471:79:80
4 HATPase_c#4
489-589 aa · 101 aa · 17.0% of protein
Raw tokenHATPase_c:489:0.0000000000131:589:110:109
  • Raw architecture: dCache_1:72:0.000022:276:213:195#HAMP:311:0.0000000000253:377:67:69#His_kinase:393:2.09e-27:471:79:80#HATPase_c:489:0.0000000000131:589:110:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003478985::NZ_QUGH01000003.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1811-5027Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWX61_04400RefSeq proteinWP_244790316.1
Context group IDGCF_003478985::NZ_QUGH01000003.1::G00031
Context members
DWX61_RS04400DWX61_RS04405
Partner locus tags
DWX61_RS04400DWX61_RS04405
Partner old locus tags
DWX61_04400DWX61_04405
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_244790316.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWX61_RS04400Primary locus identifier stored in the genes table.
Old locus tagDWX61_04400Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QUGH01000003.1Sequence record reported by the local genomic context database.
Genomic interval1 811-3 598 nt1 788 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 811-5 027 ntGCF_003478985::NZ_QUGH01000003.1::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003478985::NZ_QUGH01000003.1::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QUGH01000003.1All displayed genes belong to this local TCS context.
Neighborhood span1 811-5 027 nt3 217 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 811 nt5 027 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWX61_RS04400GCF_003478985#DWX61_RS04400
HKClassicCurrent focus

1 811-3 598 nt · Reverse (-)

Old locus DWX61_04400RefSeq WP_244790316.1
DWX61_RS04405GCF_003478985#DWX61_RS04405
RRunclassified

3 489-5 027 nt · Reverse (-)

Old locus DWX61_04405RefSeq WP_118624011.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1081878Run 6 · HK · 5 sequences
Representative sequenceGCF_003478985#DWX61_RS04400The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1081878

Simplified PFAM architecture for HKOC_1081878

PFAM domain coverage: 227 / 595 aa (38.2%)

1 aa595 aa
HAMP: 327-376 aaHAMPHis_kinase: 393-469 aaHis_kinaseHATPase_c: 490-589 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[327-376] | His_kinase[393-469] | HATPase_c[490-589]
  • Domain count: 3
  • Matched identifier: HKOC_1081878
  • Positioned domains: HAMP 327-376 ; His_kinase 393-469 ; HATPase_c 490-589
Cluster members and taxonomy
Visualization

Representative gene: GCF_003478985#DWX61_RS04400

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 293 160 · GCF_003478985
AssemblyASM347898v1 · Scaffoldhaploid
Genome composition3 953 478 bp · 43,5% GCRuminococcus sp. AF20-12LB
Signal transduction countsGenes 107 · HK 50 · RR 55CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusRuminococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Ruminococcus

Related genes

Preview from the same derived genome key