Gene detail

DWX61_RS00160

Histidine kinase, Classic

Ruminococcus sp. AF20-12LB · GCF_003478985

ClassHKTypeClassicLength596 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003478985#DWX61_RS00160Stable P2CS identifier used across views.
GenomeGCF_003478985Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Ruminococcus
Selected clusterHKOC_1075202Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_118623176.1 · MIST4 DWX61_RS00160RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length596 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage363 / 596 aa (60.9%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa596 aa
dCache_1: 175-289 aa (115 aa)1HAMP: 308-377 aa (70 aa)2His_kinase: 392-469 aa (78 aa)3HATPase_c: 493-592 aa (100 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
175-289 aa · 115 aa · 19.3% of protein
Raw tokendCache_1:175:0.0000000000733:289:115:195
2 HAMP#2
308-377 aa · 70 aa · 11.7% of protein
Raw tokenHAMP:308:0.0000000000756:377:70:69
3 His_kinase#3
392-469 aa · 78 aa · 13.1% of protein
Raw tokenHis_kinase:392:1.88e-30:469:78:80
4 HATPase_c#4
493-592 aa · 100 aa · 16.8% of protein
Raw tokenHATPase_c:493:5.06e-16:592:104:109
  • Raw architecture: dCache_1:175:0.0000000000733:289:115:195#HAMP:308:0.0000000000756:377:70:69#His_kinase:392:1.88e-30:469:78:80#HATPase_c:493:5.06e-16:592:104:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003478985::NZ_QUGH01000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span33557-36973Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWX61_00160RefSeq proteinWP_118623176.1
Context group IDGCF_003478985::NZ_QUGH01000001.1::G00001
Context members
DWX61_RS00155DWX61_RS00160
Partner locus tags
DWX61_RS00155DWX61_RS00160
Partner old locus tags
DWX61_00155DWX61_00160
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_118623176.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWX61_RS00160Primary locus identifier stored in the genes table.
Old locus tagDWX61_00160Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QUGH01000001.1Sequence record reported by the local genomic context database.
Genomic interval35 183-36 973 nt1 791 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span33 557-36 973 ntGCF_003478985::NZ_QUGH01000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003478985::NZ_QUGH01000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QUGH01000001.1All displayed genes belong to this local TCS context.
Neighborhood span33 557-36 973 nt3 417 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
33 557 nt36 973 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWX61_RS00155GCF_003478985#DWX61_RS00155
RRunclassified

33 557-35 164 nt · Reverse (-)

Old locus DWX61_00155RefSeq WP_182433919.1
DWX61_RS00160GCF_003478985#DWX61_RS00160
HKClassicCurrent focus

35 183-36 973 nt · Reverse (-)

Old locus DWX61_00160RefSeq WP_118623176.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1075202Run 6 · HK · 2 sequences
Representative sequenceGCF_003478985#DWX61_RS00160The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1075202

Simplified PFAM architecture for HKOC_1075202

PFAM domain coverage: 229 / 596 aa (38.4%)

1 aa596 aa
HAMP: 328-376 aaHAMPHis_kinase: 392-469 aaHis_kinaseHATPase_c: 493-594 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[328-376] | His_kinase[392-469] | HATPase_c[493-594]
  • Domain count: 3
  • Matched identifier: HKOC_1075202
  • Positioned domains: HAMP 328-376 ; His_kinase 392-469 ; HATPase_c 493-594
Cluster members and taxonomy
Visualization

Representative gene: GCF_003478985#DWX61_RS00160

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 293 160 · GCF_003478985
AssemblyASM347898v1 · Scaffoldhaploid
Genome composition3 953 478 bp · 43,5% GCRuminococcus sp. AF20-12LB
Signal transduction countsGenes 107 · HK 50 · RR 55CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusRuminococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Ruminococcus

Related genes

Preview from the same derived genome key