Gene detail

DWY27_RS01850

Histidine kinase, Classic

Clostridium sp. AF24-2LB · GCF_003478615

ClassHKTypeClassicLength599 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003478615#DWY27_RS01850Stable P2CS identifier used across views.
GenomeGCF_003478615Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_1058230Run 6 · 14 sequences · id 100% · cov 80%
External referencesWP_107001616.1 · A0A2T3FLP3 · MIST4 DWY27_RS01850RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length599 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage496 / 599 aa (82.8%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa599 aa
dCache_1: 47-284 aa (238 aa)1HAMP: 301-369 aa (69 aa)2His_kinase: 386-464 aa (79 aa)3HATPase_c: 480-589 aa (110 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
47-284 aa · 238 aa · 39.7% of protein
Raw tokendCache_1:47:0.000000000000171:284:244:195
2 HAMP#2
301-369 aa · 69 aa · 11.5% of protein
Raw tokenHAMP:301:0.0000000000244:369:69:69
3 His_kinase#3
386-464 aa · 79 aa · 13.2% of protein
Raw tokenHis_kinase:386:5.05e-35:464:79:80
4 HATPase_c#4
480-589 aa · 110 aa · 18.4% of protein
Raw tokenHATPase_c:480:1.62e-18:589:112:109
  • Raw architecture: dCache_1:47:0.000000000000171:284:244:195#HAMP:301:0.0000000000244:369:69:69#His_kinase:386:5.05e-35:464:79:80#HATPase_c:480:1.62e-18:589:112:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003478615::NZ_QUFT01000001.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span401628-405055Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWY27_01850RefSeq proteinWP_107001616.1
Context group IDGCF_003478615::NZ_QUFT01000001.1::G00011
Context members
DWY27_RS01845DWY27_RS01850
Partner locus tags
DWY27_RS01845DWY27_RS01850
Partner old locus tags
DWY27_01845DWY27_01850
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_107001616.1Primary protein accession used for annex mappings.
UniProt accessionA0A2T3FLP3Primary UniProt accession resolved in the annex database.
UniProt IDA0A2T3FLP3_9CLOTDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWY27_RS01850Primary locus identifier stored in the genes table.
Old locus tagDWY27_01850Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QUFT01000001.1Sequence record reported by the local genomic context database.
Genomic interval403 256-405 055 nt1 800 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span401 628-405 055 ntGCF_003478615::NZ_QUFT01000001.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003478615::NZ_QUFT01000001.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QUFT01000001.1All displayed genes belong to this local TCS context.
Neighborhood span401 628-405 055 nt3 428 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
401 628 nt405 055 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWY27_RS01845GCF_003478615#DWY27_RS01845
RRunclassified

401 628-403 256 nt · Forward (+)

Old locus DWY27_01845RefSeq WP_118472438.1
DWY27_RS01850GCF_003478615#DWY27_RS01850
HKClassicCurrent focus

403 256-405 055 nt · Forward (+)

Old locus DWY27_01850RefSeq WP_107001616.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1058230Run 6 · HK · 14 sequences
Representative sequenceGCF_003024715#C7U56_RS13300Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1058230

Simplified PFAM architecture for HKOC_1058230

PFAM domain coverage: 474 / 599 aa (79.1%)

1 aa599 aa
dCache_1: 49-283 aadCache_1HAMP: 319-369 aaHAMPHis_kinase: 386-464 aaHis_kinaseHATPase_c: 479-587 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[49-283] | HAMP[319-369] | His_kinase[386-464] | HATPase_c[479-587]
  • Domain count: 4
  • Matched identifier: HKOC_1058230
  • Positioned domains: dCache_1 49-283 ; HAMP 319-369 ; His_kinase 386-464 ; HATPase_c 479-587
Cluster members and taxonomy
Visualization

Representative gene: GCF_003024715#C7U56_RS13300

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 293 007 · GCF_003478615
AssemblyASM347861v1 · Scaffoldhaploid
Genome composition3 306 376 bp · 48,5% GCClostridium sp. AF24-2LB
Signal transduction countsGenes 59 · HK 30 · RR 27CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key