Gene detail

DW740_RS04375

Histidine kinase, Classic

Blautia obeum · GCF_003469845

ClassHKTypeClassicLength505 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003469845#DW740_RS04375Stable P2CS identifier used across views.
GenomeGCF_003469845Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1449241Run 6 · 4 sequences · id 100% · cov 80%
External referencesWP_015541924.1 · A0A414J8M3 · MIST4 DW740_RS04375RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length505 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage260 / 505 aa (51.5%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa505 aa
HAMP: 190-259 aa (70 aa)1His_kinase: 288-367 aa (80 aa)2HATPase_c: 386-495 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
190-259 aa · 70 aa · 13.9% of protein
Raw tokenHAMP:190:0.0000000000000225:259:70:69
2 His_kinase#2
288-367 aa · 80 aa · 15.8% of protein
Raw tokenHis_kinase:288:6.7e-28:367:80:80
3 HATPase_c#3
386-495 aa · 110 aa · 21.8% of protein
Raw tokenHATPase_c:386:0.000000000000334:495:115:109
  • Raw architecture: HAMP:190:0.0000000000000225:259:70:69#His_kinase:288:6.7e-28:367:80:80#HATPase_c:386:0.000000000000334:495:115:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003469845::NZ_QSKF01000003.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span29199-32353Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW740_04400RefSeq proteinWP_015541924.1
Context group IDGCF_003469845::NZ_QSKF01000003.1::G00027
Context members
DW740_RS04370DW740_RS04375
Partner locus tags
DW740_RS04370DW740_RS04375
Partner old locus tags
DW740_04395DW740_04400
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_015541924.1Primary protein accession used for annex mappings.
UniProt accessionA0A414J8M3Primary UniProt accession resolved in the annex database.
UniProt IDA0A414J8M3_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW740_RS04375Primary locus identifier stored in the genes table.
Old locus tagDW740_04400Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSKF01000003.1Sequence record reported by the local genomic context database.
Genomic interval30 836-32 353 nt1 518 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span29 199-32 353 ntGCF_003469845::NZ_QSKF01000003.1::G00027

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003469845::NZ_QSKF01000003.1::G00027

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSKF01000003.1All displayed genes belong to this local TCS context.
Neighborhood span29 199-32 353 nt3 155 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
29 199 nt32 353 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW740_RS04370GCF_003469845#DW740_RS04370
RRunclassified

29 199-30 794 nt · Reverse (-)

Old locus DW740_04395RefSeq WP_118050235.1
DW740_RS04375GCF_003469845#DW740_RS04375
HKClassicCurrent focus

30 836-32 353 nt · Reverse (-)

Old locus DW740_04400RefSeq WP_015541924.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1449241Run 6 · HK · 4 sequences
Representative sequenceGCF_000210015#CK5_RS08140Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1449241

Simplified PFAM architecture for HKOC_1449241

PFAM domain coverage: 241 / 505 aa (47.7%)

1 aa505 aa
HAMP: 206-259 aaHAMPHis_kinase: 288-364 aaHis_kinaseHATPase_c: 385-494 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[206-259] | His_kinase[288-364] | HATPase_c[385-494]
  • Domain count: 3
  • Matched identifier: HKOC_1449241
  • Positioned domains: HAMP 206-259 ; His_kinase 288-364 ; HATPase_c 385-494
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210015#CK5_RS08140

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 40 520 · GCF_003469845
AssemblyASM346984v1 · Scaffoldhaploid
Genome composition3 617 583 bp · 42,5% GCBlautia obeum
Signal transduction countsGenes 87 · HK 44 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key