Gene detail

DW856_RS02195

Histidine kinase, Hybrid

Roseburia intestinalis · GCF_003467725

ClassHKTypeHybridLength456 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_003467725#DW856_RS02195Stable P2CS identifier used across views.
GenomeGCF_003467725Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_1887798Run 6 · 3 sequences · id 100% · cov 80%
External referencesWP_147350781.1 · MIST4 DW856_RS02195RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length456 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage301 / 456 aa (66.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for DW856_RS02195
Domain-by-domain annotation3 items
1 HisKA#1
84-150 aa · 67 aa · 14.7% of protein
Raw tokenHisKA:84:4.87e-18:150:67:64
2 HATPase_c#2
197-312 aa · 116 aa · 25.4% of protein
Raw tokenHATPase_c:197:3.49e-31:312:116:109
3 Response_reg#3
334-451 aa · 118 aa · 25.9% of protein
Raw tokenResponse_reg:334:9.34e-31:451:118:111
  • Raw architecture: HisKA:84:4.87e-18:150:67:64#HATPase_c:197:3.49e-31:312:116:109#Response_reg:334:9.34e-31:451:118:111
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_003467725::NZ_QSHO01000002.1::G00026
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span53106-54476Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW856_02195RefSeq proteinWP_147350781.1
Context group IDGCF_003467725::NZ_QSHO01000002.1::G00026
Context members
DW856_RS02195
Partner locus tags
DW856_RS02195
Partner old locus tags
DW856_02195
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_147350781.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW856_RS02195Primary locus identifier stored in the genes table.
Old locus tagDW856_02195Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSHO01000002.1Sequence record reported by the local genomic context database.
Genomic interval53 106-54 476 nt1 371 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span53 106-54 476 ntGCF_003467725::NZ_QSHO01000002.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003467725::NZ_QSHO01000002.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSHO01000002.1All displayed genes belong to this local TCS context.
Neighborhood span53 106-54 476 nt1 371 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
53 106 nt54 476 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

DW856_RS02195GCF_003467725#DW856_RS02195
HKHybridCurrent focus

53 106-54 476 nt · Reverse (-)

Old locus DW856_02195RefSeq WP_147350781.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1887798Run 6 · HK · 3 sequences
Representative sequenceGCF_000209995#ROI_RS17870Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1887798

Simplified PFAM architecture for HKOC_1887798

PFAM domain coverage: 299 / 456 aa (65.6%)

1 aa456 aa
HisKA: 84-150 aaHisKAHATPase_c: 197-311 aaHATPase_cResponse_reg: 334-450 aaResponse_reg
HisKAHATPase_cResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg
  • Raw architecture: HisKA[84-150] | HATPase_c[197-311] | Response_reg[334-450]
  • Domain count: 3
  • Matched identifier: HKOC_1887798
  • Positioned domains: HisKA 84-150 ; HATPase_c 197-311 ; Response_reg 334-450
Cluster members and taxonomy
Visualization

Representative gene: GCF_000209995#ROI_RS17870

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 166 486 · GCF_003467725
AssemblyASM346772v1 · Scaffoldhaploid
Genome composition4 253 056 bp · 42,0% GCRoseburia intestinalis
Signal transduction countsGenes 106 · HK 47 · RR 56CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key