1 Response_reg#1
5-108 aa · 104 aa · 29.4% of protein
Raw token
Response_reg:5:1.74e-25:108:104:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DW856_RS01705
Response regulator, CheB family
Roseburia intestinalis · GCF_003467725
ClassRRTypeCheBLength354 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003467725#DW856_RS01705Stable P2CS identifier used across views.
GenomeGCF_003467725Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
Response_regCheB_methylest
Protein length354 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage287 / 354 aa (81.1%)Merged over positioned domains only.
Domain description1 Response_reg,1 CheB_methylestSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 CheB_methylest#2
165-347 aa · 183 aa · 51.7% of protein
Raw token
CheB_methylest:165:2.35e-79:347:183:177- Raw architecture: Response_reg:5:1.74e-25:108:104:111#CheB_methylest:165:2.35e-79:347:183:177
- Domain description: 1 Response_reg,1 CheB_methylest
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003467725::NZ_QSHO01000001.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span351261-354441Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW856_01705RefSeq proteinWP_006857473.1
Context group ID
GCF_003467725::NZ_QSHO01000001.1::G00005Context members
DW856_RS01700DW856_RS01705
Partner locus tags
DW856_RS01700DW856_RS01705
Partner old locus tags
DW856_01700DW856_01705
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_006857473.1Primary protein accession used for annex mappings.
UniProt accessionD4KW89Primary UniProt accession resolved in the annex database.
UniProt IDD4KW89_9FIRMDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDW856_RS01705Primary locus identifier stored in the genes table.
Old locus tagDW856_01705Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSHO01000001.1Sequence record reported by the local genomic context database.
Genomic interval353 377-354 441 nt1 065 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span351 261-354 441 ntGCF_003467725::NZ_QSHO01000001.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003467725::NZ_QSHO01000001.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSHO01000001.1All displayed genes belong to this local TCS context.
Neighborhood span351 261-354 441 nt3 181 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
351 261 nt354 441 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DW856_RS01700GCF_003467725#DW856_RS01700
HKCheA
351 261-353 375 nt · Reverse (-)
DW856_RS01705GCF_003467725#DW856_RS01705
RRCheBCurrent focus
353 377-354 441 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000156535#ROSINTL182_RS10535Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + CheB_methylest2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0471149
Simplified PFAM architecture for RROC_0471149
PFAM domain coverage: 289 / 354 aa (81.6%)
1 aa354 aa
Response_regCheB_methylest
- Simplified architecture: Response_reg + CheB_methylest
- Raw architecture: Response_reg[5-110] | CheB_methylest[165-347]
- Domain count: 2
- Matched identifier: RROC_0471149
- Positioned domains: Response_reg 5-110 ; Response_reg 5-110 ; CheB_methylest 165-347 ; CheB_methylest 165-347
Cluster members and taxonomy
Representative gene: GCF_000156535#ROSINTL182_RS10535
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 166 486 · GCF_003467725
AssemblyASM346772v1 · Scaffoldhaploid
Genome composition4 253 056 bp · 42,0% GCRoseburia intestinalis
Signal transduction countsGenes 106 · HK 47 · RR 56CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key