Gene detail

DXA34_RS03510

Histidine kinase, Classic

[Clostridium] symbiosum · GCF_003463485

ClassHKTypeClassicLength599 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003463485#DXA34_RS03510Stable P2CS identifier used across views.
GenomeGCF_003463485Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_1057277Run 6 · 65 sequences · id 100% · cov 80%
External referencesWP_003507818.1 · E7GKZ3 · MIST4 DXA34_RS03510RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length599 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage379 / 599 aa (63.3%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa599 aa
dCache_1: 164-284 aa (121 aa)1HAMP: 299-369 aa (71 aa)2His_kinase: 386-464 aa (79 aa)3HATPase_c: 480-587 aa (108 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
164-284 aa · 121 aa · 20.2% of protein
Raw tokendCache_1:164:0.0000000000000292:284:125:195
2 HAMP#2
299-369 aa · 71 aa · 11.9% of protein
Raw tokenHAMP:299:0.0000000000126:369:71:69
3 His_kinase#3
386-464 aa · 79 aa · 13.2% of protein
Raw tokenHis_kinase:386:1.48e-34:464:79:80
4 HATPase_c#4
480-587 aa · 108 aa · 18.0% of protein
Raw tokenHATPase_c:480:3.45e-19:587:110:109
  • Raw architecture: dCache_1:164:0.0000000000000292:284:125:195#HAMP:299:0.0000000000126:369:71:69#His_kinase:386:1.48e-34:464:79:80#HATPase_c:480:3.45e-19:587:110:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003463485::NZ_QSDB01000005.1::G00048
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span47046-50459Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDXA34_03510RefSeq proteinWP_003507818.1
Context group IDGCF_003463485::NZ_QSDB01000005.1::G00048
Context members
DXA34_RS03510DXA34_RS03515
Partner locus tags
DXA34_RS03510DXA34_RS03515
Partner old locus tags
DXA34_03510DXA34_03515
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003507818.1Primary protein accession used for annex mappings.
UniProt accessionE7GKZ3Primary UniProt accession resolved in the annex database.
UniProt IDE7GKZ3_CLOS6Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDXA34_RS03510Primary locus identifier stored in the genes table.
Old locus tagDXA34_03510Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSDB01000005.1Sequence record reported by the local genomic context database.
Genomic interval47 046-48 845 nt1 800 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span47 046-50 459 ntGCF_003463485::NZ_QSDB01000005.1::G00048

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003463485::NZ_QSDB01000005.1::G00048

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSDB01000005.1All displayed genes belong to this local TCS context.
Neighborhood span47 046-50 459 nt3 414 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
47 046 nt50 459 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DXA34_RS03510GCF_003463485#DXA34_RS03510
HKClassicCurrent focus

47 046-48 845 nt · Reverse (-)

Old locus DXA34_03510RefSeq WP_003507818.1
DXA34_RS03515GCF_003463485#DXA34_RS03515
RRunclassified

48 846-50 459 nt · Reverse (-)

Old locus DXA34_03515RefSeq WP_003507820.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1057277Run 6 · HK · 65 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS08175Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1057277

Simplified PFAM architecture for HKOC_1057277

PFAM domain coverage: 470 / 599 aa (78.5%)

1 aa599 aa
dCache_1: 53-283 aadCache_1HAMP: 319-369 aaHAMPHis_kinase: 386-464 aaHis_kinaseHATPase_c: 479-587 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[53-283] | HAMP[319-369] | His_kinase[386-464] | HATPase_c[479-587]
  • Domain count: 4
  • Matched identifier: HKOC_1057277
  • Positioned domains: dCache_1 53-283 ; HAMP 319-369 ; His_kinase 386-464 ; HATPase_c 479-587
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS08175

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 512 · GCF_003463485
AssemblyASM346348v1 · Scaffoldhaploid
Genome composition5 075 475 bp · 48,0% GC[Clostridium] symbiosum
Signal transduction countsGenes 113 · HK 55 · RR 52CheA 1 · PP 6
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key