1 dCache_1#1
164-284 aa · 121 aa · 20.2% of protein
Raw token
dCache_1:164:0.0000000000000292:284:125:195P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS08175
Histidine kinase, Classic
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeClassicLength599 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS08175Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
dCache_1HAMPHis_kinaseHATPase_c
Protein length599 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage379 / 599 aa (63.3%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa599 aa
Domain-by-domain annotation4 items
2 HAMP#2
299-369 aa · 71 aa · 11.9% of protein
Raw token
HAMP:299:0.0000000000126:369:71:693 His_kinase#3
386-464 aa · 79 aa · 13.2% of protein
Raw token
His_kinase:386:1.48e-34:464:79:804 HATPase_c#4
480-587 aa · 108 aa · 18.0% of protein
Raw token
HATPase_c:480:3.45e-19:587:110:109- Raw architecture: dCache_1:164:0.0000000000000292:284:125:195#HAMP:299:0.0000000000126:369:71:69#His_kinase:386:1.48e-34:464:79:80#HATPase_c:480:3.45e-19:587:110:109
- Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000189595::NZ_GL834307.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span330066-333479Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_01588RefSeq proteinWP_003507818.1
Context group ID
GCF_000189595::NZ_GL834307.1::G00027Context members
HMPREF9474_RS08175HMPREF9474_RS08180
Partner locus tags
HMPREF9474_RS08175HMPREF9474_RS08180
Partner old locus tags
HMPREF9474_01588HMPREF9474_01589
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003507818.1Primary protein accession used for annex mappings.
UniProt accessionE7GKZ3Primary UniProt accession resolved in the annex database.
UniProt IDE7GKZ3_CLOS6Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS08175Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_01588Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834307.1Sequence record reported by the local genomic context database.
Genomic interval330 066-331 865 nt1 800 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span330 066-333 479 ntGCF_000189595::NZ_GL834307.1::G00027
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834307.1::G00027Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834307.1All displayed genes belong to this local TCS context.
Neighborhood span330 066-333 479 nt3 414 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
330 066 nt333 479 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9474_RS08175GCF_000189595#HMPREF9474_RS08175
HKClassicCurrent focus
330 066-331 865 nt · Reverse (-)
HMPREF9474_RS08180GCF_000189595#HMPREF9474_RS08180
RRunclassified
331 866-333 479 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS08175The current gene is the representative for this cluster.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1057277
Simplified PFAM architecture for HKOC_1057277
PFAM domain coverage: 470 / 599 aa (78.5%)
1 aa599 aa
dCache_1HAMPHis_kinaseHATPase_c
- Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
- Raw architecture: dCache_1[53-283] | HAMP[319-369] | His_kinase[386-464] | HATPase_c[479-587]
- Domain count: 4
- Matched identifier: HKOC_1057277
- Positioned domains: dCache_1 53-283 ; HAMP 319-369 ; His_kinase 386-464 ; HATPase_c 479-587
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS08175
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key