Gene detail

DXC88_RS06885

Histidine kinase, Classic

Hungatella hathewayi · GCF_003437645

ClassHKTypeClassicLength597 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003437645#DXC88_RS06885Stable P2CS identifier used across views.
GenomeGCF_003437645Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_1069827Run 6 · 22 sequences · id 100% · cov 80% · representative
External referencesWP_117630855.1 · A0A374PB85 · MIST4 DXC88_RS06885RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length597 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage498 / 597 aa (83.4%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa597 aa
dCache_1: 44-281 aa (238 aa)1HAMP: 296-366 aa (71 aa)2His_kinase: 383-461 aa (79 aa)3HATPase_c: 477-586 aa (110 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
44-281 aa · 238 aa · 39.9% of protein
Raw tokendCache_1:44:0.000000000000221:281:242:195
2 HAMP#2
296-366 aa · 71 aa · 11.9% of protein
Raw tokenHAMP:296:0.00000000000761:366:71:69
3 His_kinase#3
383-461 aa · 79 aa · 13.2% of protein
Raw tokenHis_kinase:383:7.53e-34:461:79:80
4 HATPase_c#4
477-586 aa · 110 aa · 18.4% of protein
Raw tokenHATPase_c:477:2.85e-20:586:112:109
  • Raw architecture: dCache_1:44:0.000000000000221:281:242:195#HAMP:296:0.00000000000761:366:71:69#His_kinase:383:7.53e-34:461:79:80#HATPase_c:477:2.85e-20:586:112:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003437645::NZ_QSRE01000003.1::G00096
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span123384-126800Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDXC88_06885RefSeq proteinWP_117630855.1
Context group IDGCF_003437645::NZ_QSRE01000003.1::G00096
Context members
DXC88_RS06885DXC88_RS06890
Partner locus tags
DXC88_RS06885DXC88_RS06890
Partner old locus tags
DXC88_06885DXC88_06890
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_117630855.1Primary protein accession used for annex mappings.
UniProt accessionA0A374PB85Primary UniProt accession resolved in the annex database.
UniProt IDA0A374PB85_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDXC88_RS06885Primary locus identifier stored in the genes table.
Old locus tagDXC88_06885Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSRE01000003.1Sequence record reported by the local genomic context database.
Genomic interval123 384-125 177 nt1 794 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span123 384-126 800 ntGCF_003437645::NZ_QSRE01000003.1::G00096

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003437645::NZ_QSRE01000003.1::G00096

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSRE01000003.1All displayed genes belong to this local TCS context.
Neighborhood span123 384-126 800 nt3 417 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
123 384 nt126 800 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DXC88_RS06885GCF_003437645#DXC88_RS06885
HKClassicCurrent focus

123 384-125 177 nt · Reverse (-)

Old locus DXC88_06885RefSeq WP_117630855.1
DXC88_RS06890GCF_003437645#DXC88_RS06890
RRunclassified

125 178-126 800 nt · Reverse (-)

Old locus DXC88_06890RefSeq WP_002603525.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1069827Run 6 · HK · 22 sequences
Representative sequenceGCF_003437645#DXC88_RS06885The current gene is the representative for this cluster.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1069827

Simplified PFAM architecture for HKOC_1069827

PFAM domain coverage: 473 / 597 aa (79.2%)

1 aa597 aa
dCache_1: 47-280 aadCache_1HAMP: 316-366 aaHAMPHis_kinase: 383-461 aaHis_kinaseHATPase_c: 476-584 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[47-280] | HAMP[316-366] | His_kinase[383-461] | HATPase_c[476-584]
  • Domain count: 4
  • Matched identifier: HKOC_1069827
  • Positioned domains: dCache_1 47-280 ; HAMP 316-366 ; His_kinase 383-461 ; HATPase_c 476-584
Cluster members and taxonomy
Visualization

Representative gene: GCF_003437645#DXC88_RS06885

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 154 046 · GCF_003437645
AssemblyASM343764v1 · Scaffoldhaploid
Genome composition7 708 434 bp · 49,0% GCHungatella hathewayi
Signal transduction countsGenes 289 · HK 144 · RR 142CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key