Gene detail

DWY93_RS02600

Histidine kinase, Classic

Clostridium sp. AF28-12 · GCF_003435225

ClassHKTypeClassicLength575 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003435225#DWY93_RS02600Stable P2CS identifier used across views.
GenomeGCF_003435225Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_1189210Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_117469420.1 · MIST4 DWY93_RS02600RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length575 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage250 / 575 aa (43.5%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa575 aa
HAMP: 280-347 aa (68 aa)1His_kinase: 364-442 aa (79 aa)2HATPase_c: 459-561 aa (103 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
280-347 aa · 68 aa · 11.8% of protein
Raw tokenHAMP:280:0.0000000000000183:347:68:69
2 His_kinase#2
364-442 aa · 79 aa · 13.7% of protein
Raw tokenHis_kinase:364:2.61e-28:442:80:80
3 HATPase_c#3
459-561 aa · 103 aa · 17.9% of protein
Raw tokenHATPase_c:459:2.26e-16:561:108:109
  • Raw architecture: HAMP:280:0.0000000000000183:347:68:69#His_kinase:364:2.61e-28:442:80:80#HATPase_c:459:2.26e-16:561:108:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003435225::NZ_QWGJ01000002.1::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span84018-86634Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWY93_02605RefSeq proteinWP_117469420.1
Context group IDGCF_003435225::NZ_QWGJ01000002.1::G00023
Context members
DWY93_RS02600DWY93_RS02605
Partner locus tags
DWY93_RS02600DWY93_RS02605
Partner old locus tags
DWY93_02605DWY93_02610
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_117469420.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWY93_RS02600Primary locus identifier stored in the genes table.
Old locus tagDWY93_02605Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWGJ01000002.1Sequence record reported by the local genomic context database.
Genomic interval84 018-85 745 nt1 728 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span84 018-86 634 ntGCF_003435225::NZ_QWGJ01000002.1::G00023

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003435225::NZ_QWGJ01000002.1::G00023

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWGJ01000002.1All displayed genes belong to this local TCS context.
Neighborhood span84 018-86 634 nt2 617 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
84 018 nt86 634 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWY93_RS02600GCF_003435225#DWY93_RS02600
HKClassicCurrent focus

84 018-85 745 nt · Forward (+)

Old locus DWY93_02605RefSeq WP_117469420.1
DWY93_RS02605GCF_003435225#DWY93_RS02605
RRunclassified

85 786-86 634 nt · Forward (+)

Old locus DWY93_02610RefSeq WP_117469421.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1189210Run 6 · HK · 1 sequences
Representative sequenceGCF_003435225#DWY93_RS02600The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1189210

Simplified PFAM architecture for HKOC_1189210

PFAM domain coverage: 229 / 575 aa (39.8%)

1 aa575 aa
HAMP: 299-347 aaHAMPHis_kinase: 365-442 aaHis_kinaseHATPase_c: 460-561 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[299-347] | His_kinase[365-442] | HATPase_c[460-561]
  • Domain count: 3
  • Matched identifier: HKOC_1189210
  • Positioned domains: HAMP 299-347 ; His_kinase 365-442 ; HATPase_c 460-561
Cluster members and taxonomy
Visualization

Representative gene: GCF_003435225#DWY93_RS02600

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 305 241 · GCF_003435225
AssemblyASM343522v1 · Scaffoldhaploid
Genome composition3 514 663 bp · 48,5% GCClostridium sp. AF28-12
Signal transduction countsGenes 67 · HK 31 · RR 34CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key