Gene detail

DWY93_RS02485

Histidine kinase, Classic

Clostridium sp. AF28-12 · GCF_003435225

ClassHKTypeClassicLength599 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003435225#DWY93_RS02485Stable P2CS identifier used across views.
GenomeGCF_003435225Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_1058347Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_117471737.1 · MIST4 DWY93_RS02485RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length599 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage366 / 599 aa (61.1%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa599 aa
dCache_1: 171-280 aa (110 aa)1HAMP: 298-367 aa (70 aa)2His_kinase: 383-461 aa (79 aa)3HATPase_c: 477-583 aa (107 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
171-280 aa · 110 aa · 18.4% of protein
Raw tokendCache_1:171:6.25e-16:280:114:195
2 HAMP#2
298-367 aa · 70 aa · 11.7% of protein
Raw tokenHAMP:298:0.0000000000748:367:70:69
3 His_kinase#3
383-461 aa · 79 aa · 13.2% of protein
Raw tokenHis_kinase:383:5.63e-35:461:79:80
4 HATPase_c#4
477-583 aa · 107 aa · 17.9% of protein
Raw tokenHATPase_c:477:1.07e-16:583:109:109
  • Raw architecture: dCache_1:171:6.25e-16:280:114:195#HAMP:298:0.0000000000748:367:70:69#His_kinase:383:5.63e-35:461:79:80#HATPase_c:477:1.07e-16:583:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003435225::NZ_QWGJ01000002.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span52369-55829Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWY93_02490RefSeq proteinWP_117471737.1
Context group IDGCF_003435225::NZ_QWGJ01000002.1::G00022
Context members
DWY93_RS02480DWY93_RS02485
Partner locus tags
DWY93_RS02480DWY93_RS02485
Partner old locus tags
DWY93_02485DWY93_02490
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_117471737.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWY93_RS02485Primary locus identifier stored in the genes table.
Old locus tagDWY93_02490Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWGJ01000002.1Sequence record reported by the local genomic context database.
Genomic interval54 030-55 829 nt1 800 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span52 369-55 829 ntGCF_003435225::NZ_QWGJ01000002.1::G00022

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003435225::NZ_QWGJ01000002.1::G00022

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWGJ01000002.1All displayed genes belong to this local TCS context.
Neighborhood span52 369-55 829 nt3 461 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
52 369 nt55 829 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWY93_RS02480GCF_003435225#DWY93_RS02480
RRunclassified

52 369-54 009 nt · Forward (+)

Old locus DWY93_02485RefSeq WP_117471736.1
DWY93_RS02485GCF_003435225#DWY93_RS02485
HKClassicCurrent focus

54 030-55 829 nt · Forward (+)

Old locus DWY93_02490RefSeq WP_117471737.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1058347Run 6 · HK · 1 sequences
Representative sequenceGCF_003435225#DWY93_RS02485The current gene is the representative for this cluster.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1058347

Simplified PFAM architecture for HKOC_1058347

PFAM domain coverage: 470 / 599 aa (78.5%)

1 aa599 aa
dCache_1: 48-280 aadCache_1HAMP: 316-366 aaHAMPHis_kinase: 383-461 aaHis_kinaseHATPase_c: 477-583 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[48-280] | HAMP[316-366] | His_kinase[383-461] | HATPase_c[477-583]
  • Domain count: 4
  • Matched identifier: HKOC_1058347
  • Positioned domains: dCache_1 48-280 ; HAMP 316-366 ; His_kinase 383-461 ; HATPase_c 477-583
Cluster members and taxonomy
Visualization

Representative gene: GCF_003435225#DWY93_RS02485

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 305 241 · GCF_003435225
AssemblyASM343522v1 · Scaffoldhaploid
Genome composition3 514 663 bp · 48,5% GCClostridium sp. AF28-12
Signal transduction countsGenes 67 · HK 31 · RR 34CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key