1 HAMP#1
50-120 aa · 71 aa · 20.5% of protein
Raw token
HAMP:50:0.00000000000285:120:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DW677_RS04375
Histidine kinase, Classic
Clostridium sp. AM25-23AC · GCF_003435125
ClassHKTypeClassicLength347 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003435125#DW677_RS04375Stable P2CS identifier used across views.
GenomeGCF_003435125Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length347 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 347 aa (70.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa347 aa
Domain-by-domain annotation3 items
2 HisKA#2
127-189 aa · 63 aa · 18.2% of protein
Raw token
HisKA:127:3.54e-16:189:63:643 HATPase_c#3
233-343 aa · 111 aa · 32.0% of protein
Raw token
HATPase_c:233:2.32e-28:343:111:109- Raw architecture: HAMP:50:0.00000000000285:120:71:69#HisKA:127:3.54e-16:189:63:64#HATPase_c:233:2.32e-28:343:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003435125::NZ_QWGI01000004.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span184697-186450Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW677_04375RefSeq proteinWP_117566539.1
Context group ID
GCF_003435125::NZ_QWGI01000004.1::G00029Context members
DW677_RS04375DW677_RS04380
Partner locus tags
DW677_RS04375DW677_RS04380
Partner old locus tags
DW677_04375DW677_04380
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_117566539.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDW677_RS04375Primary locus identifier stored in the genes table.
Old locus tagDW677_04375Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWGI01000004.1Sequence record reported by the local genomic context database.
Genomic interval184 697-185 740 nt1 044 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span184 697-186 450 ntGCF_003435125::NZ_QWGI01000004.1::G00029
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003435125::NZ_QWGI01000004.1::G00029Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWGI01000004.1All displayed genes belong to this local TCS context.
Neighborhood span184 697-186 450 nt1 754 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
184 697 nt186 450 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DW677_RS04375GCF_003435125#DW677_RS04375
HKClassicCurrent focus
184 697-185 740 nt · Reverse (-)
DW677_RS04380GCF_003435125#DW677_RS04380
RROmpR
185 740-186 450 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003435125#DW677_RS04375The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2811486
Simplified PFAM architecture for HKOC_2811486
PFAM domain coverage: 224 / 347 aa (64.6%)
1 aa347 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[68-120] | HisKA[126-188] | HATPase_c[235-342]
- Domain count: 3
- Matched identifier: HKOC_2811486
- Positioned domains: HAMP 68-120 ; HisKA 126-188 ; HATPase_c 235-342
Cluster members and taxonomy
Representative gene: GCF_003435125#DW677_RS04375
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 2 305 240 · GCF_003435125
AssemblyASM343512v1 · Scaffoldhaploid
Genome composition3 757 782 bp · 48,0% GCClostridium sp. AM25-23AC
Signal transduction countsGenes 66 · HK 30 · RR 34CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium
Related genes
Preview from the same derived genome key