Gene detail

C4N24_RS11965

Histidine kinase, Hybrid

Faecalibacterium prausnitzii · GCF_003287405

ClassHKTypeHybridLength948 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_003287405#C4N24_RS11965Stable P2CS identifier used across views.
GenomeGCF_003287405Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Faecalibacterium
Selected clusterHKOC_0330830Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_112091602.1 · A0A329U526 · MIST4 C4N24_RS11965RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PBPbHisKAHATPase_cResponse_reg
Protein length948 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage720 / 948 aa (75.9%)Merged over positioned domains only.
Domain description2 PBPb,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa948 aa
PBPb: 45-262 aa (218 aa)1PBPb: 284-486 aa (203 aa)2HisKA: 573-638 aa (66 aa)3HATPase_c: 685-803 aa (119 aa)4Response_reg: 828-941 aa (114 aa)5
Domain-by-domain annotation5 items
1 PBPb#1
45-262 aa · 218 aa · 23.0% of protein
Raw tokenPBPb:45:8.98e-29:262:231:219
2 PBPb#2
284-486 aa · 203 aa · 21.4% of protein
Raw tokenPBPb:284:0.0000000000123:486:220:219
3 HisKA#3
573-638 aa · 66 aa · 7.0% of protein
Raw tokenHisKA:573:5.64e-17:638:66:64
4 HATPase_c#4
685-803 aa · 119 aa · 12.6% of protein
Raw tokenHATPase_c:685:3.01e-28:803:119:109
5 Response_reg#5
828-941 aa · 114 aa · 12.0% of protein
Raw tokenResponse_reg:828:2.53e-30:941:114:111
  • Raw architecture: PBPb:45:8.98e-29:262:231:219#PBPb:284:0.0000000000123:486:220:219#HisKA:573:5.64e-17:638:66:64#HATPase_c:685:3.01e-28:803:119:109#Response_reg:828:2.53e-30:941:114:111
  • Domain description: 2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_003287405::NZ_PRLD01000013.1::G00003
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span30479-33325Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC4N24_11955RefSeq proteinWP_112091602.1
Context group IDGCF_003287405::NZ_PRLD01000013.1::G00003
Context members
C4N24_RS11965
Partner locus tags
C4N24_RS11965
Partner old locus tags
C4N24_11955
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_112091602.1Primary protein accession used for annex mappings.
UniProt accessionA0A329U526Primary UniProt accession resolved in the annex database.
UniProt IDA0A329U526_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC4N24_RS11965Primary locus identifier stored in the genes table.
Old locus tagC4N24_11955Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PRLD01000013.1Sequence record reported by the local genomic context database.
Genomic interval30 479-33 325 nt2 847 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span30 479-33 325 ntGCF_003287405::NZ_PRLD01000013.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003287405::NZ_PRLD01000013.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PRLD01000013.1All displayed genes belong to this local TCS context.
Neighborhood span30 479-33 325 nt2 847 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
30 479 nt33 325 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

C4N24_RS11965GCF_003287405#C4N24_RS11965
HKHybridCurrent focus

30 479-33 325 nt · Forward (+)

Old locus C4N24_11955RefSeq WP_112091602.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0330830Run 6 · HK · 1 sequences
Representative sequenceGCF_003287405#C4N24_RS11965The current gene is the representative for this cluster.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0330830

Simplified PFAM architecture for HKOC_0330830

PFAM domain coverage: 507 / 948 aa (53.5%)

1 aa948 aa
SBP_bac_3: 54-262 aaSBP_bac_3HisKA: 573-638 aaHisKAHATPase_c: 686-801 aaHATPase_cResponse_reg: 828-943 aaResponse_reg
SBP_bac_3HisKAHATPase_cResponse_reg
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c + Response_reg
  • Raw architecture: SBP_bac_3[54-262] | HisKA[573-638] | HATPase_c[686-801] | Response_reg[828-943]
  • Domain count: 4
  • Matched identifier: HKOC_0330830
  • Positioned domains: SBP_bac_3 54-262 ; HisKA 573-638 ; HATPase_c 686-801 ; Response_reg 828-943
Cluster members and taxonomy
Visualization

Representative gene: GCF_003287405#C4N24_RS11965

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 853 · GCF_003287405
AssemblyASM328740v1 · Contighaploid
Genome composition3 032 382 bp · 56,0% GCFaecalibacterium prausnitzii
Signal transduction countsGenes 58 · HK 26 · RR 30CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusFaecalibacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Faecalibacterium

Related genes

Preview from the same derived genome key