Gene detail

CDL25_RS10485

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_002865355

ClassHKTypeClassicLength583 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002865355#CDL25_RS10485Stable P2CS identifier used across views.
GenomeGCF_002865355Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1147261Run 6 · 151 sequences · id 100% · cov 80%
External referencesWP_004844762.1 · A7B8B0 · MIST4 CDL25_RS10485RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length583 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage252 / 583 aa (43.2%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa583 aa
HAMP: 288-357 aa (70 aa)1His_kinase: 372-452 aa (81 aa)2HATPase_c: 475-575 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
288-357 aa · 70 aa · 12.0% of protein
Raw tokenHAMP:288:0.00000000212:357:70:69
2 His_kinase#2
372-452 aa · 81 aa · 13.9% of protein
Raw tokenHis_kinase:372:3.78e-22:452:81:80
3 HATPase_c#3
475-575 aa · 101 aa · 17.3% of protein
Raw tokenHATPase_c:475:0.000000000000116:575:105:109
  • Raw architecture: HAMP:288:0.00000000212:357:70:69#His_kinase:372:3.78e-22:452:81:80#HATPase_c:475:0.000000000000116:575:105:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002865355::NZ_NIHR01000018.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span48717-51526Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDL25_10475RefSeq proteinWP_004844762.1
Context group IDGCF_002865355::NZ_NIHR01000018.1::G00016
Context members
CDL25_RS10485CDL25_RS10490
Partner locus tags
CDL25_RS10485CDL25_RS10490
Partner old locus tags
CDL25_10475CDL25_10480
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004844762.1Primary protein accession used for annex mappings.
UniProt accessionA7B8B0Primary UniProt accession resolved in the annex database.
UniProt IDA7B8B0_MEDG7Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDL25_RS10485Primary locus identifier stored in the genes table.
Old locus tagCDL25_10475Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NIHR01000018.1Sequence record reported by the local genomic context database.
Genomic interval48 717-50 468 nt1 752 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span48 717-51 526 ntGCF_002865355::NZ_NIHR01000018.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002865355::NZ_NIHR01000018.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NIHR01000018.1All displayed genes belong to this local TCS context.
Neighborhood span48 717-51 526 nt2 810 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
48 717 nt51 526 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDL25_RS10485GCF_002865355#CDL25_RS10485
HKClassicCurrent focus

48 717-50 468 nt · Forward (+)

Old locus CDL25_10475RefSeq WP_004844762.1
CDL25_RS10490GCF_002865355#CDL25_RS10490
RRunclassified

50 456-51 526 nt · Forward (+)

Old locus CDL25_10480RefSeq WP_009244307.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1147261Run 6 · HK · 151 sequences
Representative sequenceGCF_000169475#RUMGNA_RS16720Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1147261

Simplified PFAM architecture for HKOC_1147261

PFAM domain coverage: 183 / 583 aa (31.4%)

1 aa583 aa
His_kinase: 372-451 aaHis_kinaseHATPase_c: 472-574 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[372-451] | HATPase_c[472-574]
  • Domain count: 2
  • Matched identifier: HKOC_1147261
  • Positioned domains: His_kinase 372-451 ; HATPase_c 472-574
Cluster members and taxonomy
Visualization

Representative gene: GCF_000169475#RUMGNA_RS16720

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 151 total members. Page 1 / 4.

GCF_000169475#RUMGNA_RS16720 (representative)
RUMGNA_RS16720 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_000507805#HMPREF1201_RS12305
HMPREF1201_RS12305 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_001406655#ARA00_RS07195
ARA00_RS07195 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_002865355#CDL25_RS10485
CDL25_RS10485 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_002865425#CCY17_RS02890
CCY17_RS02890 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_002865465#CDL19_RS10505
CDL19_RS10505 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_002959615#C5Y99_RS04425
C5Y99_RS04425 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003436535#DXD36_RS02115
DXD36_RS02115 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003457855#DWY88_RS11565
DWY88_RS11565 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003459125#DWY23_RS04585
DWY23_RS04585 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003459705#DWX36_RS14000
DWX36_RS14000 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003464875#DWV82_RS09500
DWV82_RS09500 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003467625#DW865_RS12380
DW865_RS12380 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003468635#DW812_RS08510
DW812_RS08510 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003469585#DW722_RS02270
DW722_RS02270 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003470485#DW248_RS00845
DW248_RS00845 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003471005#DW270_RS05970
DW270_RS05970 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003471265#DW243_RS00195
DW243_RS00195 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003471625#DW207_RS08140
DW207_RS08140 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003473045#DW153_RS15670
DW153_RS15670 · HK · Classic
RefSeq: WP_243037748.1
GCF_003473185#DW142_RS13485
DW142_RS13485 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003475065#DWZ70_RS03515
DWZ70_RS03515 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_003475365#DWZ50_RS15280
DWZ50_RS15280 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_008121495#FXV78_RS16745
FXV78_RS16745 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_009831375#RGna_RS04325
RGna_RS04325 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013299595#G4396_RS05420
G4396_RS05420 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013299785#G4415_RS11745
G4415_RS11745 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013300015#G4394_RS03040
G4394_RS03040 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013300525#G4386_RS03230
G4386_RS03230 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013302885#G4951_RS09915
G4951_RS09915 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303255#G4975_RS02585
G4975_RS02585 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303285#G4954_RS10135
G4954_RS10135 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303345#G4989_RS02585
G4989_RS02585 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303355#G4971_RS02585
G4971_RS02585 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303395#G4976_RS02585
G4976_RS02585 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303435#G4970_RS00105
G4970_RS00105 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303465#G4978_RS02585
G4978_RS02585 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303495#G4977_RS02590
G4977_RS02590 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303515#G4958_RS03145
G4958_RS03145 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303565#G4950_RS03230
G4950_RS03230 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303595#G4963_RS03035
G4963_RS03035 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303605#G4962_RS11545
G4962_RS11545 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303625#G4947_RS09800
G4947_RS09800 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303665#G5A18_RS12495
G5A18_RS12495 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303675#G4983_RS12215
G4983_RS12215 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303685#G4986_RS11910
G4986_RS11910 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303695#G4993_RS11595
G4993_RS11595 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303705#G5A17_RS12155
G5A17_RS12155 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303765#G4999_RS12085
G4999_RS12085 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0
GCF_013303805#G4981_RS13330
G4981_RS13330 · HK · Classic
RefSeq: WP_004844762.1
UniProt: A7B8B0

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_002865355
AssemblyASM286535v1 · Scaffoldhaploid
Genome composition3 415 781 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 83 · HK 39 · RR 43CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key