1 HAMP#1
288-357 aa · 70 aa · 12.0% of protein
Raw token
HAMP:288:0.00000000212:357:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1201_RS12305
Histidine kinase, Classic
Mediterraneibacter gnavus CC55_001C · GCF_000507805
ClassHKTypeClassicLength583 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000507805#HMPREF1201_RS12305Stable P2CS identifier used across views.
GenomeGCF_000507805Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length583 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage252 / 583 aa (43.2%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa583 aa
Domain-by-domain annotation3 items
2 His_kinase#2
372-452 aa · 81 aa · 13.9% of protein
Raw token
His_kinase:372:3.78e-22:452:81:803 HATPase_c#3
475-575 aa · 101 aa · 17.3% of protein
Raw token
HATPase_c:475:0.000000000000116:575:105:109- Raw architecture: HAMP:288:0.00000000212:357:70:69#His_kinase:372:3.78e-22:452:81:80#HATPase_c:475:0.000000000000116:575:105:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000507805::NZ_KI669417.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span76279-79088Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1201_02482RefSeq proteinWP_004844762.1
Context group ID
GCF_000507805::NZ_KI669417.1::G00039Context members
HMPREF1201_RS12300HMPREF1201_RS12305
Partner locus tags
HMPREF1201_RS12300HMPREF1201_RS12305
Partner old locus tags
HMPREF1201_02481HMPREF1201_02482
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_004844762.1Primary protein accession used for annex mappings.
UniProt accessionA7B8B0Primary UniProt accession resolved in the annex database.
UniProt IDA7B8B0_MEDG7Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1201_RS12305Primary locus identifier stored in the genes table.
Old locus tagHMPREF1201_02482Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI669417.1Sequence record reported by the local genomic context database.
Genomic interval77 337-79 088 nt1 752 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span76 279-79 088 ntGCF_000507805::NZ_KI669417.1::G00039
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000507805::NZ_KI669417.1::G00039Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI669417.1All displayed genes belong to this local TCS context.
Neighborhood span76 279-79 088 nt2 810 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
76 279 nt79 088 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1201_RS12300GCF_000507805#HMPREF1201_RS12300
RRunclassified
76 279-77 349 nt · Reverse (-)
HMPREF1201_RS12305GCF_000507805#HMPREF1201_RS12305
HKClassicCurrent focus
77 337-79 088 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000169475#RUMGNA_RS16720Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1147261
Simplified PFAM architecture for HKOC_1147261
PFAM domain coverage: 183 / 583 aa (31.4%)
1 aa583 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[372-451] | HATPase_c[472-574]
- Domain count: 2
- Matched identifier: HKOC_1147261
- Positioned domains: His_kinase 372-451 ; HATPase_c 472-574
Cluster members and taxonomy
Representative gene: GCF_000169475#RUMGNA_RS16720
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 073 375 · GCF_000507805
AssemblyRumi_gnav_CC55_001C_V1 · Scaffoldhaploid
Genome composition3 181 861 bp · 43,0% GCMediterraneibacter gnavus CC55_001C
Signal transduction countsGenes 78 · HK 37 · RR 40CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key