Gene detail

COE23_RS02225

Histidine kinase, CheA

Bacillus cereus · GCF_002585905

ClassHKTypeCheALength662 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002585905#COE23_RS02225Stable P2CS identifier used across views.
GenomeGCF_002585905Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_0867576Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_098988052.1 · MIST4 COE23_RS02225RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length662 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage426 / 662 aa (64.4%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa662 aa
Hpt: 4-96 aa (93 aa)1H-kinase_dim: 279-338 aa (60 aa)2HATPase_c: 386-525 aa (140 aa)3CheW: 530-662 aa (133 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
4-96 aa · 93 aa · 14.0% of protein
Raw tokenHpt:4:5.9e-17:96:93:84
2 H-kinase_dim#2
279-338 aa · 60 aa · 9.1% of protein
Raw tokenH-kinase_dim:279:0.0000000104:338:67:67
3 HATPase_c#3
386-525 aa · 140 aa · 21.1% of protein
Raw tokenHATPase_c:386:3.22e-17:525:140:109
4 CheW#4
530-662 aa · 133 aa · 20.1% of protein
Raw tokenCheW:530:2.17e-22:662:139:138
  • Raw architecture: Hpt:4:5.9e-17:96:93:84#H-kinase_dim:279:0.0000000104:338:67:67#HATPase_c:386:3.22e-17:525:140:109#CheW:530:2.17e-22:662:139:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002585905::NZ_NUOX01000002.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span171656-174140Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCOE23_02225RefSeq proteinWP_098988052.1
Context group IDGCF_002585905::NZ_NUOX01000002.1::G00032
Context members
COE23_RS02220COE23_RS02225
Partner locus tags
COE23_RS02220COE23_RS02225
Partner old locus tags
COE23_02220COE23_02225
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_098988052.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCOE23_RS02225Primary locus identifier stored in the genes table.
Old locus tagCOE23_02225Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NUOX01000002.1Sequence record reported by the local genomic context database.
Genomic interval172 152-174 140 nt1 989 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span171 656-174 140 ntGCF_002585905::NZ_NUOX01000002.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002585905::NZ_NUOX01000002.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NUOX01000002.1All displayed genes belong to this local TCS context.
Neighborhood span171 656-174 140 nt2 485 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
171 656 nt174 140 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

COE23_RS02220GCF_002585905#COE23_RS02220
RRCheY

171 656-172 024 nt · Forward (+)

Old locus COE23_02220RefSeq WP_000940577.1
COE23_RS02225GCF_002585905#COE23_RS02225
HKCheACurrent focus

172 152-174 140 nt · Forward (+)

Old locus COE23_02225RefSeq WP_098988052.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0867576Run 6 · HK · 1 sequences
Representative sequenceGCF_002585905#COE23_RS02225The current gene is the representative for this cluster.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0867576

Simplified PFAM architecture for HKOC_0867576

PFAM domain coverage: 509 / 662 aa (76.9%)

1 aa662 aa
Hpt: 4-103 aaHptP2: 148-225 aaP2H-kinase_dim: 279-337 aaH-kinase_dimHATPase_c: 386-525 aaHATPase_cCheW: 531-662 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[4-103] | P2[148-225] | H-kinase_dim[279-337] | HATPase_c[386-525] | CheW[531-662]
  • Domain count: 5
  • Matched identifier: HKOC_0867576
  • Positioned domains: Hpt 4-103 ; P2 148-225 ; H-kinase_dim 279-337 ; HATPase_c 386-525 ; CheW 531-662
Cluster members and taxonomy
Visualization

Representative gene: GCF_002585905#COE23_RS02225

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 396 · GCF_002585905
AssemblyASM258590v1 · Scaffoldhaploid
Genome composition5 424 615 bp · 35,0% GCBacillus cereus
Signal transduction countsGenes 112 · HK 62 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key