Gene detail

AWN56_RS08200

Histidine kinase, Classic

Enterococcus faecium · GCF_001543565

ClassHKTypeClassicLength574 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001543565#AWN56_RS08200Stable P2CS identifier used across views.
GenomeGCF_001543565Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1192861Run 6 · 370 sequences · id 100% · cov 80%
External referencesWP_002297733.1 · A0A829F5Y4 · MIST4 AWN56_RS08200RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length574 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage255 / 574 aa (44.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa574 aa
HAMP: 287-357 aa (71 aa)1His_kinase: 372-450 aa (79 aa)2HATPase_c: 469-573 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
287-357 aa · 71 aa · 12.4% of protein
Raw tokenHAMP:287:0.000000644:357:71:69
2 His_kinase#2
372-450 aa · 79 aa · 13.8% of protein
Raw tokenHis_kinase:372:2.53e-28:450:80:80
3 HATPase_c#3
469-573 aa · 105 aa · 18.3% of protein
Raw tokenHATPase_c:469:0.000000000176:573:108:109
  • Raw architecture: HAMP:287:0.000000644:357:71:69#His_kinase:372:2.53e-28:450:80:80#HATPase_c:469:0.000000000176:573:108:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001543565::NZ_LRAV01000141.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span21387-24559Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAWN56_08220RefSeq proteinWP_002297733.1
Context group IDGCF_001543565::NZ_LRAV01000141.1::G00013
Context members
AWN56_RS08200AWN56_RS08205
Partner locus tags
AWN56_RS08200AWN56_RS08205
Partner old locus tags
AWN56_08220AWN56_08225
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002297733.1Primary protein accession used for annex mappings.
UniProt accessionA0A829F5Y4Primary UniProt accession resolved in the annex database.
UniProt IDA0A829F5Y4_ENTFCDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAWN56_RS08200Primary locus identifier stored in the genes table.
Old locus tagAWN56_08220Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LRAV01000141.1Sequence record reported by the local genomic context database.
Genomic interval21 387-23 111 nt1 725 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span21 387-24 559 ntGCF_001543565::NZ_LRAV01000141.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001543565::NZ_LRAV01000141.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LRAV01000141.1All displayed genes belong to this local TCS context.
Neighborhood span21 387-24 559 nt3 173 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
21 387 nt24 559 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

AWN56_RS08200GCF_001543565#AWN56_RS08200
HKClassicCurrent focus

21 387-23 111 nt · Forward (+)

Old locus AWN56_08220RefSeq WP_002297733.1
AWN56_RS08205GCF_001543565#AWN56_RS08205
RRunclassified

23 108-24 559 nt · Forward (+)

Old locus AWN56_08225RefSeq WP_002317568.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1192861Run 6 · HK · 370 sequences
Representative sequenceGCF_000172835#EFME1636_RS06035Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1192861

Simplified PFAM architecture for HKOC_1192861

PFAM domain coverage: 224 / 574 aa (39.0%)

1 aa574 aa
HAMP: 316-357 aaHAMPHis_kinase: 372-449 aaHis_kinaseHATPase_c: 469-572 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[316-357] | His_kinase[372-449] | HATPase_c[469-572]
  • Domain count: 3
  • Matched identifier: HKOC_1192861
  • Positioned domains: HAMP 316-357 ; His_kinase 372-449 ; HATPase_c 469-572
Cluster members and taxonomy
Visualization

Representative gene: GCF_000172835#EFME1636_RS06035

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 352 · GCF_001543565
AssemblyASM154356v1 · Scaffoldhaploid
Genome composition3 016 176 bp · 38,0% GCEnterococcus faecium
Signal transduction countsGenes 42 · HK 20 · RR 22CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key