1 dCache_1#1
82-278 aa · 197 aa · 32.8% of protein
Raw token
dCache_1:82:0.00000000281:278:206:195P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
M72_RS03775
Histidine kinase, Classic
Roseburia faecis · GCF_001406815
ClassHKTypeClassicLength601 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001406815#M72_RS03775Stable P2CS identifier used across views.
GenomeGCF_001406815Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
dCache_1HAMPHis_kinaseHATPase_c
Protein length601 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage446 / 601 aa (74.2%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa601 aa
Domain-by-domain annotation4 items
2 HAMP#2
297-358 aa · 62 aa · 10.3% of protein
Raw token
HAMP:297:0.0000579:358:62:693 His_kinase#3
380-459 aa · 80 aa · 13.3% of protein
Raw token
His_kinase:380:6.57e-34:459:80:804 HATPase_c#4
475-581 aa · 107 aa · 17.8% of protein
Raw token
HATPase_c:475:5.86e-17:581:110:109- Raw architecture: dCache_1:82:0.00000000281:278:206:195#HAMP:297:0.0000579:358:62:69#His_kinase:380:6.57e-34:459:80:80#HATPase_c:475:5.86e-17:581:110:109
- Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_001406815::NZ_CVRR01000007.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span39664-43054Genomic interval covered by the local TCS group.
Identifiers
Old locus tagM72_22201RefSeq proteinWP_082413759.1
Context group ID
GCF_001406815::NZ_CVRR01000007.1::G00022Context members
M72_RS03770M72_RS03775
Partner locus tags
M72_RS03770M72_RS03775
Partner old locus tags
M72_22191M72_22201
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_082413759.1Primary protein accession used for annex mappings.
UniProt accessionA0A0M6WHJ5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0M6WHJ5_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagM72_RS03775Primary locus identifier stored in the genes table.
Old locus tagM72_22201Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CVRR01000007.1Sequence record reported by the local genomic context database.
Genomic interval41 249-43 054 nt1 806 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span39 664-43 054 ntGCF_001406815::NZ_CVRR01000007.1::G00022
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_001406815::NZ_CVRR01000007.1::G00022Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CVRR01000007.1All displayed genes belong to this local TCS context.
Neighborhood span39 664-43 054 nt3 391 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
39 664 nt43 054 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
M72_RS03770GCF_001406815#M72_RS03770
RRunclassified
39 664-41 268 nt · Forward (+)
M72_RS03775GCF_001406815#M72_RS03775
HKClassicCurrent focus
41 249-43 054 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_001406815#M72_RS03775The current gene is the representative for this cluster.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1048005
Simplified PFAM architecture for HKOC_1048005
PFAM domain coverage: 414 / 601 aa (68.9%)
1 aa601 aa
dCache_1His_kinaseHATPase_c
- Simplified architecture: dCache_1 + His_kinase + HATPase_c
- Raw architecture: dCache_1[48-277] | His_kinase[381-459] | HATPase_c[477-581]
- Domain count: 3
- Matched identifier: HKOC_1048005
- Positioned domains: dCache_1 48-277 ; His_kinase 381-459 ; HATPase_c 477-581
Cluster members and taxonomy
Representative gene: GCF_001406815#M72_RS03775
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 301 302 · GCF_001406815
AssemblyM72 · Contighaploid
Genome composition3 334 694 bp · 43,0% GCRoseburia faecis
Signal transduction countsGenes 110 · HK 47 · RR 61CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key