1 sCache_like#1
72-131 aa · 60 aa · 13.5% of protein
Raw token
sCache_like:72:0.0000537:131:60:114P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
M72_RS02445
Histidine kinase, Classic
Roseburia faecis · GCF_001406815
ClassHKTypeClassicLength443 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001406815#M72_RS02445Stable P2CS identifier used across views.
GenomeGCF_001406815Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
sCache_likeHisKAHATPase_c
Protein length443 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage233 / 443 aa (52.6%)Merged over positioned domains only.
Domain description1 sCache_like,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa443 aa
Domain-by-domain annotation3 items
2 HisKA#2
225-290 aa · 66 aa · 14.9% of protein
Raw token
HisKA:225:5.36e-17:290:67:643 HATPase_c#3
335-441 aa · 107 aa · 24.2% of protein
Raw token
HATPase_c:335:4.58e-32:441:107:109- Raw architecture: sCache_like:72:0.0000537:131:60:114#HisKA:225:5.36e-17:290:67:64#HATPase_c:335:4.58e-32:441:107:109
- Domain description: 1 sCache_like,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_001406815::NZ_CVRR01000005.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span320999-323008Genomic interval covered by the local TCS group.
Identifiers
Old locus tagM72_02901RefSeq proteinWP_055067037.1
Context group ID
GCF_001406815::NZ_CVRR01000005.1::G00014Context members
M72_RS02445M72_RS02450
Partner locus tags
M72_RS02445M72_RS02450
Partner old locus tags
M72_02901M72_02911
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_055067037.1Primary protein accession used for annex mappings.
UniProt accessionA0A0M6WCL8Primary UniProt accession resolved in the annex database.
UniProt IDA0A0M6WCL8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagM72_RS02445Primary locus identifier stored in the genes table.
Old locus tagM72_02901Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CVRR01000005.1Sequence record reported by the local genomic context database.
Genomic interval320 999-322 330 nt1 332 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span320 999-323 008 ntGCF_001406815::NZ_CVRR01000005.1::G00014
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_001406815::NZ_CVRR01000005.1::G00014Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CVRR01000005.1All displayed genes belong to this local TCS context.
Neighborhood span320 999-323 008 nt2 010 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
320 999 nt323 008 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
M72_RS02445GCF_001406815#M72_RS02445
HKClassicCurrent focus
320 999-322 330 nt · Reverse (-)
M72_RS02450GCF_001406815#M72_RS02450
RROmpR
322 340-323 008 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_001406815#M72_RS02445The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2042652
Simplified PFAM architecture for HKOC_2042652
PFAM domain coverage: 170 / 443 aa (38.4%)
1 aa443 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[225-290] | HATPase_c[338-441]
- Domain count: 2
- Matched identifier: HKOC_2042652
- Positioned domains: HisKA 225-290 ; HATPase_c 338-441
Cluster members and taxonomy
Representative gene: GCF_001406815#M72_RS02445
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 301 302 · GCF_001406815
AssemblyM72 · Contighaploid
Genome composition3 334 694 bp · 43,0% GCRoseburia faecis
Signal transduction countsGenes 110 · HK 47 · RR 61CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key