1 HAMP#1
289-358 aa · 70 aa · 11.5% of protein
Raw token
HAMP:289:0.0000000053:358:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
M72_RS01225
Histidine kinase, Classic
Roseburia faecis · GCF_001406815
ClassHKTypeClassicLength607 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001406815#M72_RS01225Stable P2CS identifier used across views.
GenomeGCF_001406815Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length607 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage254 / 607 aa (41.8%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa607 aa
Domain-by-domain annotation3 items
2 His_kinase#2
380-459 aa · 80 aa · 13.2% of protein
Raw token
His_kinase:380:1.3e-31:459:80:803 HATPase_c#3
483-586 aa · 104 aa · 17.1% of protein
Raw token
HATPase_c:483:0.00000123:586:105:109- Raw architecture: HAMP:289:0.0000000053:358:70:69#His_kinase:380:1.3e-31:459:80:80#HATPase_c:483:0.00000123:586:105:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_001406815::NZ_CVRR01000005.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span43764-47170Genomic interval covered by the local TCS group.
Identifiers
Old locus tagM72_00421RefSeq proteinWP_022046038.1
Context group ID
GCF_001406815::NZ_CVRR01000005.1::G00009Context members
M72_RS01220M72_RS01225
Partner locus tags
M72_RS01220M72_RS01225
Partner old locus tags
M72_00411M72_00421
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_022046038.1Primary protein accession used for annex mappings.
UniProt accessionA0A0M6WDH7Primary UniProt accession resolved in the annex database.
UniProt IDA0A0M6WDH7_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagM72_RS01225Primary locus identifier stored in the genes table.
Old locus tagM72_00421Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CVRR01000005.1Sequence record reported by the local genomic context database.
Genomic interval45 347-47 170 nt1 824 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span43 764-47 170 ntGCF_001406815::NZ_CVRR01000005.1::G00009
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_001406815::NZ_CVRR01000005.1::G00009Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CVRR01000005.1All displayed genes belong to this local TCS context.
Neighborhood span43 764-47 170 nt3 407 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
43 764 nt47 170 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
M72_RS01220GCF_001406815#M72_RS01220
RRunclassified
43 764-45 353 nt · Reverse (-)
M72_RS01225GCF_001406815#M72_RS01225
HKClassicCurrent focus
45 347-47 170 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_001406815#M72_RS01225The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1019181
Simplified PFAM architecture for HKOC_1019181
PFAM domain coverage: 237 / 607 aa (39.0%)
1 aa607 aa
HAMPHis_kinaseHATPase_c
- Simplified architecture: HAMP + His_kinase + HATPase_c
- Raw architecture: HAMP[306-356] | His_kinase[380-459] | HATPase_c[481-586]
- Domain count: 3
- Matched identifier: HKOC_1019181
- Positioned domains: HAMP 306-356 ; His_kinase 380-459 ; HATPase_c 481-586
Cluster members and taxonomy
Representative gene: GCF_001406815#M72_RS01225
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 301 302 · GCF_001406815
AssemblyM72 · Contighaploid
Genome composition3 334 694 bp · 43,0% GCRoseburia faecis
Signal transduction countsGenes 110 · HK 47 · RR 61CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key