Gene detail

BREU_RS03075

Histidine kinase, Classic

Bifidobacterium reuteri DSM 23975 · GCF_000741695

ClassHKTypeClassicLength968 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000741695#BREU_RS03075Stable P2CS identifier used across views.
GenomeGCF_000741695Bacteria; Bacillati; Actinomycetota; Actinomycetes; Bifidobacteriales; Bifidobacteriaceae; Bifidobacterium
Selected clusterHKOC_0313232Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_081886519.1 · A0A087CUU9 · MIST4 BREU_RS03075RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDHisKAHATPase_c
Protein length968 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage388 / 968 aa (40.1%)Merged over positioned domains only.
Domain description1 KdpD,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa968 aa
KdpD: 4-213 aa (210 aa)1HisKA: 622-689 aa (68 aa)2HATPase_c: 731-840 aa (110 aa)3
Domain-by-domain annotation3 items
1 KdpD#1
4-213 aa · 210 aa · 21.7% of protein
Raw tokenKdpD:4:1.49e-126:213:210:210
2 HisKA#2
622-689 aa · 68 aa · 7.0% of protein
Raw tokenHisKA:622:0.0000000000254:689:68:64
3 HATPase_c#3
731-840 aa · 110 aa · 11.4% of protein
Raw tokenHATPase_c:731:2.72e-24:840:110:109
  • Raw architecture: KdpD:4:1.49e-126:213:210:210#HisKA:622:0.0000000000254:689:68:64#HATPase_c:731:2.72e-24:840:110:109
  • Domain description: 1 KdpD,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000741695::NZ_JGZK01000003.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span72487-76109Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBREU_0064RefSeq proteinWP_081886519.1
Context group IDGCF_000741695::NZ_JGZK01000003.1::G00003
Context members
BREU_RS03070BREU_RS03075
Partner locus tags
BREU_RS03070BREU_RS03075
Partner old locus tags
BREU_0063BREU_0064
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_081886519.1Primary protein accession used for annex mappings.
UniProt accessionA0A087CUU9Primary UniProt accession resolved in the annex database.
UniProt IDA0A087CUU9_9BIFIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBREU_RS03075Primary locus identifier stored in the genes table.
Old locus tagBREU_0064Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JGZK01000003.1Sequence record reported by the local genomic context database.
Genomic interval73 203-76 109 nt2 907 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span72 487-76 109 ntGCF_000741695::NZ_JGZK01000003.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000741695::NZ_JGZK01000003.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JGZK01000003.1All displayed genes belong to this local TCS context.
Neighborhood span72 487-76 109 nt3 623 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
72 487 nt76 109 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BREU_RS03070GCF_000741695#BREU_RS03070
RROmpR

72 487-73 200 nt · Reverse (-)

Old locus BREU_0063RefSeq WP_044088256.1
BREU_RS03075GCF_000741695#BREU_RS03075
HKClassicCurrent focus

73 203-76 109 nt · Reverse (-)

Old locus BREU_0064RefSeq WP_081886519.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0313232Run 6 · HK · 5 sequences
Representative sequenceGCF_000741695#BREU_RS03075The current gene is the representative for this cluster.
PFAM architectureKdpD + Usp + DUF4118 + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0313232

Simplified PFAM architecture for HKOC_0313232

PFAM domain coverage: 605 / 968 aa (62.5%)

1 aa968 aa
KdpD: 5-213 aaKdpDUsp: 234-349 aaUspDUF4118: 386-490 aaDUF4118HisKA: 623-689 aaHisKAHATPase_c: 732-839 aaHATPase_c
KdpDUspDUF4118HisKAHATPase_c
  • Simplified architecture: KdpD + Usp + DUF4118 + HisKA + HATPase_c
  • Raw architecture: KdpD[5-213] | Usp[234-349] | DUF4118[386-490] | HisKA[623-689] | HATPase_c[732-839]
  • Domain count: 5
  • Matched identifier: HKOC_0313232
  • Positioned domains: KdpD 5-213 ; Usp 234-349 ; DUF4118 386-490 ; HisKA 623-689 ; HATPase_c 732-839
Cluster members and taxonomy
Visualization

Representative gene: GCF_000741695#BREU_RS03075

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 437 610 · GCF_000741695
AssemblyBifreu · Contighaploid
Genome composition2 847 572 bp · 60,5% GCBifidobacterium reuteri DSM 23975
Signal transduction countsGenes 39 · HK 15 · RR 20CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumActinomycetotaClassActinomycetesOrderBifidobacterialesFamilyBifidobacteriaceaeGenusBifidobacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Actinomycetota4Actinomycetes5Bifidobacteriales6Bifidobacteriaceae7Bifidobacterium

Related genes

Preview from the same derived genome key