1 HAMP#1
298-367 aa · 70 aa · 11.9% of protein
Raw token
HAMP:298:0.0000000191:367:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF0373_RS02420
Histidine kinase, Classic
Eubacterium ramulus ATCC 29099 · GCF_000469345
ClassHKTypeClassicLength589 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000469345#HMPREF0373_RS02420Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length589 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage253 / 589 aa (43.0%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa589 aa
Domain-by-domain annotation3 items
2 His_kinase#2
382-461 aa · 80 aa · 13.6% of protein
Raw token
His_kinase:382:3.26e-28:461:80:803 HATPase_c#3
479-581 aa · 103 aa · 17.5% of protein
Raw token
HATPase_c:479:1.66e-16:581:110:109- Raw architecture: HAMP:298:0.0000000191:367:70:69#His_kinase:382:3.26e-28:461:80:80#HATPase_c:479:1.66e-16:581:110:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000469345::NZ_KI271092.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3598-6892Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_02697RefSeq proteinWP_021737980.1
Context group ID
GCF_000469345::NZ_KI271092.1::G00009Context members
HMPREF0373_RS02420HMPREF0373_RS02425
Partner locus tags
HMPREF0373_RS02420HMPREF0373_RS02425
Partner old locus tags
HMPREF0373_02697HMPREF0373_02698
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021737980.1Primary protein accession used for annex mappings.
UniProt accessionU2QVG8Primary UniProt accession resolved in the annex database.
UniProt IDU2QVG8_EUBRADisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF0373_RS02420Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_02697Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271092.1Sequence record reported by the local genomic context database.
Genomic interval3 598-5 367 nt1 770 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 598-6 892 ntGCF_000469345::NZ_KI271092.1::G00009
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000469345::NZ_KI271092.1::G00009Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271092.1All displayed genes belong to this local TCS context.
Neighborhood span3 598-6 892 nt3 295 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 598 nt6 892 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF0373_RS02420GCF_000469345#HMPREF0373_RS02420
HKClassicCurrent focus
3 598-5 367 nt · Reverse (-)
HMPREF0373_RS02425GCF_000469345#HMPREF0373_RS02425
RRunclassified
5 345-6 892 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000469345#HMPREF0373_RS02420The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1115028
Simplified PFAM architecture for HKOC_1115028
PFAM domain coverage: 182 / 589 aa (30.9%)
1 aa589 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[382-461] | HATPase_c[480-581]
- Domain count: 2
- Matched identifier: HKOC_1115028
- Positioned domains: His_kinase 382-461 ; HATPase_c 480-581
Cluster members and taxonomy
Representative gene: GCF_000469345#HMPREF0373_RS02420
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium
Related genes
Preview from the same derived genome key