Gene detail

HMPREF0373_RS01125

Histidine kinase, Hybrid

Eubacterium ramulus ATCC 29099 · GCF_000469345

ClassHKTypeHybridLength954 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000469345#HMPREF0373_RS01125Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_0322851Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_021737701.1 · U2Q467 · MIST4 HMPREF0373_RS01125RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_cResponse_reg
Protein length954 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage728 / 954 aa (76.3%)Merged over positioned domains only.
Domain description2 SBP_bac_3,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa954 aa
SBP_bac_3: 44-260 aa (217 aa)1SBP_bac_3: 282-486 aa (205 aa)2HisKA: 571-639 aa (69 aa)3HATPase_c: 685-803 aa (119 aa)4Response_reg: 829-946 aa (118 aa)5
Domain-by-domain annotation5 items
1 SBP_bac_3#1
44-260 aa · 217 aa · 22.7% of protein
Raw tokenSBP_bac_3:44:1.43e-33:260:227:224
2 SBP_bac_3#2
282-486 aa · 205 aa · 21.5% of protein
Raw tokenSBP_bac_3:282:0.00000000000601:486:220:224
3 HisKA#3
571-639 aa · 69 aa · 7.2% of protein
Raw tokenHisKA:571:7.47e-19:639:69:64
4 HATPase_c#4
685-803 aa · 119 aa · 12.5% of protein
Raw tokenHATPase_c:685:1.96e-29:803:119:109
5 Response_reg#5
829-946 aa · 118 aa · 12.4% of protein
Raw tokenResponse_reg:829:1.07e-30:946:118:111
  • Raw architecture: SBP_bac_3:44:1.43e-33:260:227:224#SBP_bac_3:282:0.00000000000601:486:220:224#HisKA:571:7.47e-19:639:69:64#HATPase_c:685:1.96e-29:803:119:109#Response_reg:829:1.07e-30:946:118:111
  • Domain description: 2 SBP_bac_3,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000469345::NZ_KI271080.1::G00003
Group size22 locus tags listed below.
HK / RR2 / 0Counts resolved for the local TCS neighborhood.
Context span1738-6807Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_00502RefSeq proteinWP_021737701.1
Context group IDGCF_000469345::NZ_KI271080.1::G00003
Context members
HMPREF0373_RS01125HMPREF0373_RS01130
Partner locus tags
HMPREF0373_RS01125HMPREF0373_RS01130
Partner old locus tags
HMPREF0373_00502HMPREF0373_00503
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021737701.1Primary protein accession used for annex mappings.
UniProt accessionU2Q467Primary UniProt accession resolved in the annex database.
UniProt IDU2Q467_EUBRADisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0373_RS01125Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_00502Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271080.1Sequence record reported by the local genomic context database.
Genomic interval1 738-4 602 nt2 865 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 738-6 807 ntGCF_000469345::NZ_KI271080.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000469345::NZ_KI271080.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271080.1All displayed genes belong to this local TCS context.
Neighborhood span1 738-6 807 nt5 070 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 738 nt6 807 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF0373_RS01130GCF_000469345#HMPREF0373_RS01130
HKHybrid

4 645-6 807 nt · Reverse (-)

Old locus HMPREF0373_00503RefSeq WP_021737702.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0322851Run 6 · HK · 2 sequences
Representative sequenceGCF_000469345#HMPREF0373_RS01125The current gene is the representative for this cluster.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0322851

Simplified PFAM architecture for HKOC_0322851

PFAM domain coverage: 519 / 954 aa (54.4%)

1 aa954 aa
SBP_bac_3: 45-261 aaSBP_bac_3HisKA: 571-639 aaHisKAHATPase_c: 686-801 aaHATPase_cResponse_reg: 829-945 aaResponse_reg
SBP_bac_3HisKAHATPase_cResponse_reg
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c + Response_reg
  • Raw architecture: SBP_bac_3[45-261] | HisKA[571-639] | HATPase_c[686-801] | Response_reg[829-945]
  • Domain count: 4
  • Matched identifier: HKOC_0322851
  • Positioned domains: SBP_bac_3 45-261 ; HisKA 571-639 ; HATPase_c 686-801 ; Response_reg 829-945
Cluster members and taxonomy
Visualization

Representative gene: GCF_000469345#HMPREF0373_RS01125

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key