Gene detail

HMPREF0373_RS01140

Histidine kinase, Hybrid

Eubacterium ramulus ATCC 29099 · GCF_000469345

ClassHKTypeHybridLength983 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000469345#HMPREF0373_RS01140Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_0303811Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_044962544.1 · MIST4 HMPREF0373_RS01140RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_9HisKAHATPase_cResponse_reg
Protein length983 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage520 / 983 aa (52.9%)Merged over positioned domains only.
Domain description1 PAS_9,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa983 aa
PAS_9: 346-448 aa (103 aa)1HisKA: 470-536 aa (67 aa)2HATPase_c: 584-701 aa (118 aa)3Response_reg: 720-833 aa (114 aa)4Response_reg: 861-978 aa (118 aa)5
Domain-by-domain annotation5 items
1 PAS_9#1
346-448 aa · 103 aa · 10.5% of protein
Raw tokenPAS_9:346:0.0000218:448:107:102
2 HisKA#2
470-536 aa · 67 aa · 6.8% of protein
Raw tokenHisKA:470:6.31e-20:536:67:64
3 HATPase_c#3
584-701 aa · 118 aa · 12.0% of protein
Raw tokenHATPase_c:584:7.79e-33:701:118:109
4 Response_reg#4
720-833 aa · 114 aa · 11.6% of protein
Raw tokenResponse_reg:720:1.53e-19:833:114:111
5 Response_reg#5
861-978 aa · 118 aa · 12.0% of protein
Raw tokenResponse_reg:861:2.98e-33:978:118:111
  • Raw architecture: PAS_9:346:0.0000218:448:107:102#HisKA:470:6.31e-20:536:67:64#HATPase_c:584:7.79e-33:701:118:109#Response_reg:720:1.53e-19:833:114:111#Response_reg:861:2.98e-33:978:118:111
  • Domain description: 1 PAS_9,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000469345::NZ_KI271080.1::G00004
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span7745-10696Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_00505RefSeq proteinWP_044962544.1
Context group IDGCF_000469345::NZ_KI271080.1::G00004
Context members
HMPREF0373_RS01140
Partner locus tags
HMPREF0373_RS01140
Partner old locus tags
HMPREF0373_00505
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_044962544.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0373_RS01140Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_00505Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271080.1Sequence record reported by the local genomic context database.
Genomic interval7 745-10 696 nt2 952 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span7 745-10 696 ntGCF_000469345::NZ_KI271080.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000469345::NZ_KI271080.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271080.1All displayed genes belong to this local TCS context.
Neighborhood span7 745-10 696 nt2 952 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 745 nt10 696 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0303811Run 6 · HK · 2 sequences
Representative sequenceGCF_000469345#HMPREF0373_RS01140The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0303811

Simplified PFAM architecture for HKOC_0303811

PFAM domain coverage: 414 / 983 aa (42.1%)

1 aa983 aa
HisKA: 470-536 aaHisKAHATPase_c: 584-700 aaHATPase_cResponse_reg: 720-832 aaResponse_regResponse_reg: 861-977 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[470-536] | HATPase_c[584-700] | Response_reg[720-832] | Response_reg[861-977]
  • Domain count: 4
  • Matched identifier: HKOC_0303811
  • Positioned domains: HisKA 470-536 ; HATPase_c 584-700 ; Response_reg 720-832 ; Response_reg 861-977
Cluster members and taxonomy
Visualization

Representative gene: GCF_000469345#HMPREF0373_RS01140

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key